#ppiposseofpicks: 24-27 (.471)
#ppiupsetalert: 4-8 (.333)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | BTN | #5 Ohio State | Southeast Missouri State | 29 | 31 | |
| 7 PM | ESPN+ | #13 Dayton | North Texas | 15.5 | 19 | |
| 8:30 PM | ACCN | #19 Florida State | North Florida | 20.5 | 16 | |
| 11 PM | PAC12 | #22 Washington | Seattle | 16 | 17 | |
| 9:30 PM | ESPNU | Temple (N) | Miami (FL) (N) | 2.5 | 1 | |
| 7 PM | East Carolina | Maryland-Eastern Shore | 16 | 7 | #ppiposseofpicks: MD-Eastern Shore +16 | |
| 8:30 PM | FS1 | Creighton | Oklahoma | 3.5 | -2 | #ppiposseofpicks: Oklahoma +155 |
| 6:30 PM | FS1 | Georgetown | UMBC | 17 | 25 | #ppiposseofpicks: Georgetown -17 |
| 7 PM | ESPN2 | Florida (N) | Provdidence (N) | 5 | 9 | |
| 8 PM | Marquette | Grambling State | 24 | 20 | ||
| 9 PM | ESPN2 | Ohio | Purdue | -10 | 1 | #ppiposseofpicks: Ohio +450 |