#ppiposseofpicks: 46-49 (.484)
#ppiupsetalert: 8-8 (.500)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 11:30 AM | ESPN2 | #4 Duke | Brown | 27.5 | 25 | |
| 1:30 PM | ESPN2 | #9 Memphis | New Orleans | 25.5 | 22 | #ppiposseofpicks: New Orleans +25.5 |
| 2 PM | ACCNX | #17 Florida State | North Alabama | 25 | 23 | |
| 3:45 PM | CBS | #19 Kentucky | #3 Louisville | 1.5 | -3 | #ppiupsetalert, #ppiposseofpicks: Kentucky -135 |
| 4 PM | FS`1 | #12 Butler | Louisiana Monroe | 23 | 28 | #ppiposseofpicks: Butler -23 |
| 7 PM | #15 San Diego State | Cal Poly | 26.5 | 37 | #ppiposseofpicks: San Diego St -26.5 | |
| 2 PM | ESPN+ | La Salle | Bucknell | 6.5 | 14 | #ppiposseofpicks: La Salle -6.5 |
| 4 PM | ESPN+ | George Washington | Longwood | 8.5 | 9 | |
| 7 PM | ACCNX | Syracuse | Niagara | 22 | 23 | |
| 4 PM | ESPN3 | East Carolina | Eastern Kentucky | 10 | 8 | |
| 12 PM | FS1 | Georgetown | American University | 18 | 23 | #ppiposseofpicks: Georgetown -18 |
| 2 PM | FS1 | Marquette | Central Arkansas | 24.5 | 24 | |
| 6 PM | Montana State | Sacramento State | 1 | 1 | ||
| 12 PM | BTN | Purdue | Central Michigan | 20 | 16 | |
| 1:30 PM | CBS | Tennessee | Wisconsin | 3.5 | 9 | #ppiposseofpicks: Tennessee -3.5 |
| 4 PM | BTN | Minnesota | Florida Intl | 12.5 | 12 | |
| 3 PM | PAC12 | Arizona State | Texas Southern | 17 | 15 | |
| 5 PM | PAC12 | UCLA | Cal State Fullerton | 14 | 17 | |
| 12 PM | SECN | Florida | Long Beach State | 22.5 | 21 |