#ppiposseofpicks: 54-61 (.470)
#ppiupsetalert: 9-9 (.500)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 3 PM | ESPN+ | #7 Baylor | Jackson State | 30 | 23 | #ppiposseofpicks: Jackson State +30 |
| 6:30 PM | FS1 | #10 Villanova | Xavier | 6 | 1 | #ppiupsetalert, #ppiposseofpicks: Xavier +210 |
| 7 PM | ESPN+ | #18 Dayton | North Florida | 20 | 21 | |
| 9 PM | #1 Gonzaga | Detroit Mercy | 32.5 | 36 | ||
| 9 PM | CBSSN | #9 Memphis | Tulane | 15.5 | 12 | |
| 7 PM | ESPN3 | Akron | Massachusetts | 9.5 | 9 | |
| 7 PM | ESPN+ | Fordham | Coppin State | 8 | 4 | |
| 7 PM | ESPN+ | Buffalo | St. Bonaventure | 2.5 | 2 | |
| 8 PM | SECN+ | Vanderbilt | Davidson | 1 | 1 | |
| 9 PM | TCU | George Mason | 11 | 0 | #ppiposseofpicks: George Mason +500 | |
| 12 PM | ACCNX | Pittsburgh | Canisius | 14 | 13 | |
| 7 PM | ACCN | North Carolina | Yale | 8 | 2 | #ppiposseofpicks: Yale +200 |
| 7 PM | Oklahoma | UT-Rio Grande Valley | 20 | 24 | ||
| 8 PM | LHN | Texas | High Point | 25 | 24 | |
| 8:30 PM | FS1 | DePaul | Seton Hall | 1 | 7 | #ppiposseofpicks: DePaul -1 |
| 9 PM | Montana State | Northern ARizona | 4 | 8 | ||
| 3 PM | SECN+ | South Carolina | Stetson | 21 | 21 | |
| 7 PM | SECN+ | Georgia | Austin Peay | 12.5 | 9 | |
| 8 PM | SECN+ | Mississippi State | Kent State | 7.5 | 7 | |
| 8 PM | SECN+ | Missouri | Chicago State | 33.5 | 27 | #ppiposseofpicks: Chicago State +33.5 |
| 8 PM | SECN+ | Texas A&M | Texas Southern | 9.5 | 7 |