#ppiposseofpicks: 71-94 (.430)
#ppiupsetalert: 16-18 (.414)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7:30 PM | ACCNX | Wake Forest | #10 Florida State | -7 | -7 | |
| 8 PM | ESPN+ | Iowa State | #3 Kansas | -6.5 | -6 | |
| 9 PM | ACCN | Georgia Tech | #2 Duke | -12 | -8 | #ppiposseofpicks: Georgia Tech +12 |
| 9 PM | SECN | #5 Auburn | Vanderbilt | 16 | 17 | |
| 9 PM | Wyoming | #7 San Diego State | -17 | -24 | #ppiposseofpicks: SDSU -17 | |
| 7 PM | ESPN+ | Saint Joseph’s | Duquesne | -7.5 | -12 | #ppiposseofpicks: Duquesne -7.5 |
| 7 PM | CBSSN | Rhode Island | Davidson | 3 | 5 | |
| 7 PM | George Mason | St. Bonaventure | 3 | 10 | ||
| 7 PM | ESPN+ | Massachusetts | La Salle | 1.5 | -3 | #ppiposseofpicks: La Salle +102 |
| 8 PM | ESPN+ | Saint Louis | George Washington | 11.5 | 21 | |
| 9 PM | CBSSN | Connecticut | Tulane | 11 | 4 | #ppiposseofpicks: Tulane +11 |
| 7 PM | ESPNU | Cincinnati | Tulsa | 9.5 | 6 | |
| 8 PM | ESPN3 | SMU | UCF | 6.5 | 9 | |
| 9 PM | ESPN2 | Texas | Oklahoma | 2 | 0 | #closegamealert, ppiposseofpicks: Oklahoma +135 |
| 6:30 PM | FS1 | Georgetown | St. John’s | 4 | 9 | #ppiposseofpicks: Georgetown -4 |
| 8:30 PM | FS1 | Xavier | Seton Hall | 2.5 | 2 | |
| 7 PM | BTN | Indiana | Northwestern | 12.5 | 15 | |
| 9 PM | BTN | Wisconsin | Illinois | 4 | 5 | |
| 7 PM | SECN | Alabama | Mississippi State | 3 | 5 | |
| 9 PM | ESPNU | LSU | Arkansas | 5 | -2 | #ppiposseofpicks: Arkansas +170 |