#ppiposseofpicks: 131-163 (.446)
#ppiupsetalert: 39-49 (.443)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | BTN | Purdue | #13 Penn State | 4.5 | 2 | #ppiupsetalert, Penn St +4.5 |
| 7 PM | ESPN | Vanderbilt | #12 Kentucky | -12 | -10 | |
| 7:30 PM | CBSSN | #6 Dayton | Rhode Island | 9.5 | 9 | |
| 8:30 PM | BTN | #9 Maryland | Nebraska | 16.5 | 23 | |
| 9 PM | ESPN | #22 Illinois | Michigan State | -1.5 | 2 | #ppiupsetalert, Illinois +1.5 |
| 9 PM | SECN | #25 LSU | Missouri | 11 | 12 | |
| 11 PM | ESPN2 | #4 San Diego State | New Mexico | 15.5 | 18 | |
| 7 PM | ESPN+ | Saint Joseph’s | St. Bonaventure | -8 | -9 | |
| 7 PM | ESPN+ | Davidson | Fordham | 14.5 | 11 | |
| 7 PM | ESPN2 | Syracuse | NC State | 4.5 | 5 | |
| 8 PM | ACCN | Wake Forest | North Carolina | -2 | 3 | Wake Forest +2 |
| 9 PM | ESPN2 | Virginia | Notre Dame | 5.5 | 4 | |
| 9 PM | ESPNU | Kansas State | Oklahoma State | 3.5 | 0 | |
| 7 PM | ESPN+ | Ball State | Northern Illinois | 8 | 4 | |
| 7 PM | ESPNU | Ole Miss | Mississippi State | -2 | -2 | |
| 7 PM | SECN | Tennessee | Arkansas | 2.5 | 0 | #closegamealert |