#ppiposseofpicks: 151-177 (.460)
#ppiupsetalert: 45-57 (.441)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | FS1 | #9 Penn State | Illinois | 6.5 | 9 | |
| 7 PM | ESPN2 | #17 West Virginia | Oklahoma State | 10.5 | 10 | |
| 8 PM | BTN | #7 Maryland | Northwestern | 14 | 23 | Maryland -14 |
| 8 PM | ACCN | #8 Florida State | Pittsburgh | 11 | 14 | |
| 8:30 PM | CBSSN | VCU | #5 Dayton | -3 | -4 | #ppiupsetalert, VCU +3 |
| 8:30 PM | FS1 | #19 Marquette | #15 Creighton | 3 | 0 | #ppiupsetalert, Marquette -155 |
| 9 PM | ESPN2 | Oklahoma | #1 Baylor | -3 | -5 | |
| 9 PM | ESPN | LSU | #10 Kentucky | 2.5 | 1 | #ppiupsetalert, LSU -145 |
| 6:30 PM | SECN | Tennessee | Vanderbilt | 13 | 11 | |
| 6:30 PM | CBSSN | Saint Joseph’s | Davidson | -12.5 | -8 | Saint Joseph’s +12.5 |
| 7 PM | ESPN+ | Massachusetts | Saint Louis | -3 | -5 | |
| 7 PM | ESPN+ | Buffalo | Ball State | 4.5 | 5 | |
| 7 PM | ESPN | Wisconsin | Purdue | 4 | 3 | |
| 7 PM | ESPNU | Florida | Arkansas | 7.5 | 5 | |
| 8:30 PM | SECN | Missouri | Ole Miss | 1.5 | 3 |