#ppiposseofpicks: 162-186 (.466)
#ppiupsetalert: 51-61 (.456)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN | #8 Florida State | #11 Louisville | 2.5 | 3 | #ppiupsetalert, Louisville +2.5 |
| 7 PM | ESPNU | Texas | #17 West Virginia | -5.5 | -2 | #ppiupsetalert, Texas +5.5 |
| 9 PM | ESPN | #3 Kansas | Oklahoma State | 14.5 | 18 | Kansas -14.5 |
| 8 PM | BTN | Illinois | Nebraska | 13.5 | 17 | Ilinois -13.5 |