#ppiupsetalert record: 2-5 (.286)
| Time | Chan | Home | Away | Spread | Margin | |
| 12 PM | ESPN2 | #3 Kansas | #8 Texas | 4.5 | 3 | |
| 12 PM | FOX | Providence | #11 Creighton | -4 | 2 | #ppiupsetalert, Providence +160 |
| 12 PM | CBS | Arkansas | #12 Missouri | 6.5 | 3 | #ppiupsetalert, Arkansas -280 |
| 1 PM | ESPN+ | Iowa State | #2 Baylor | -15.5 | -14 | |
| 2 PM | ESPN2 | #14 Rutgers | #10 Iowa | -3.5 | 4 | #ppiupsetalert, Rutgers +145 |
| 4 PM | ESPN2 | Oklahoma | #9 West Virginia | 2 | -9 | West Virginia +2 |
| 4 PM | ESPN+ | #13 Texas Tech | Oklahoma State | 8.5 | 3 | Oklahoma State +320, #ppiupsetalert |
| 6 PM | ESPN2 | #7 Tennessee | Alabama | 9.5 | 6 | Alabama +9.5 |
| 6 PM | BTN | #15 Illinois | Purdue | 8 | 8 | |
| 8 PM | BTN | Nebraska | #17 Michigan State | -8 | 3 | Nebraska +285, #ppiupsetalert |
| 10 PM | Gonzaga | San Francisco | 19 | 14 | San Francisco +19 | |
| 10 PM | Oregon | Stanford | 5.5 | 9 | Oregon -5.5 | |
| 2 PM | ESPNU | Kansas State | TCU | -3.5 | -11 | TCU -3.5 |
| 4:30 PM | FS1 | Seton Hall | Butler | 9 | 21 | Seton Hall -9 |
| 7:30 PM | CBSSN | Georgetown | Marquette | -4.5 | -3 | |
| 12 PM | ACCNX | Boston College | Louisville | -6.5 | -7 | |
| 2 PM | ACCNX | North Carolina | Notre Dame | 10 | 12 | |
| 2 PM | ACCNX | Miami (FL) | Clemson | -4 | -11 | Clemson -4 |
| 4 PM | PAC12 | USC | Utah | 5 | 11 | USC -5 |
| 6 PM | PAC12 | Oregon State | California | 2 | 0 | |
| 8 PM | PAC12 | UCLA | Colorado | 2.5 | 1 | |
| 10:30 PM | PAC12 | Washington State | Arizona | -8 | 3 | Washington State +320 |
| 2 PM | CBS | Florida | LSU | 1 | 5 | Florida -1 |
| 3:30 PM | SECN | South Carolina | Florida A&M | 20.5 | 8 | Florida A&M +20.5 |
| 6 PM | SECN | Mississippi State | Kentucky | -1.5 | 14 | Mississippi State +1.5 |
| 6 PM | ESPNU | Ole Miss | Wichita State | 7.5 | 3 | Wichita State +7.5 |
| 8:30 PM | SECN | Texas A&M | Auburn | 1.5 | -1 | Auburn +105 |
| 3 PM | CBSSN | Ball State | Ohio | -1 | 8 | Ball State +1 |