#ppiupsetalert record: 6-19 (.240)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | #14 Illinois | #21 Ohio State | 6.5 | 7 | ||
| 1 PM | SECN | Texas A&M | #17 Missouri | -4.5 | -5 | Texas A&M +4.5, #ppiupsetalert |
| 2 PM | ESPN2 | #23 Minnesota | #7 Michigan | -5.5 | -4 | Minnesota +5.5, #ppiupsetalert |
| 4 PM | ESPN | #15 Texas Tech | #2 Baylor | -4 | -2 | Texas Tech +4, #ppiupsetalert |
| 4 PM | FS1 | Butler | #8 Creighton | -8 | -12 | Creighton -8 |
| 6 PM | SECN | #10 Tennessee | Vanderbilt | 18 | 16 | |
| 6 PM | ESPN | #12 Clemson | #18 Virginia | -2 | 6 | #ppiupsetalert, Clemson +2 |
| 8 PM | ESPN | Saint Mary’s | #1 Gonzaga | -15.5 | -8 | Saint Mary’s +15.5 |
| 8 PM | LHN | #4 Texas | Kansas State | 18 | 24 | Texas -18 |
| 8 PM | ACCN | Miami (FL) | #16 Louisville | -3.5 | -8 | Louisville -3.5 |
| 12 PM | ACCNX | Pittsburgh | Syracuse | -4.5 | 5 | Pittsburgh +175 |
| 12 PM | ESPN | Florida State | North Carolina | 4.5 | 1 | North Carolina +4.5 |
| 12 PM | ESPN2 | Ole Miss | Georgia | 8 | 3 | Georgia +8 |
| 1 PM | ESPN+ | Ball State | Northern Illinois | 10.5 | 16 | Ball State -10.5 |
| 2 PM | St. John’s | Marquette | -2.5 | 4 | St. John’s +120 | |
| 2 PM | ESPN | Auburn | Kentucky | 3 | 5 | Auburn -1.5 |
| 2:05 PM | Montana State | Portland State | 6.5 | 13 | Montana State -6.5 | |
| 3 PM | PAC12 | Colorado | Stanford | 7.5 | 9 | |
| 3:30 PM | SECN | Alabama | Arkansas | 2 | 12 | Alabama -2 |
| 4 PM | ACCN | Notre Dame | Boston College | 5 | 4 | |
| 4 PM | ESPN2 | Mississippi State | Florida | 0 | 4 | Mississippi State -110 |
| 5 PM | PAC12 | UCLA | Washington | 15 | 25 | UCLA -15 |
| 7 PM | Oregon State | Arizona State | -6 | 1 | Oregon State +220 | |
| 8:30 PM | SECN | LSU | South Carolina | 8 | 12 | LSU -8 |
| 9:30 PM | USC | Washington State | 13 | 11 | ||
| 10 PM | ESPNU | Utah | California | 12 | 7 | California +12 |