#ppiupsetalert record: 51-45 (.531)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN | #2 Michigan | Michigan State | 12 | 17 | Michigan -12, #MSUBubble |
| 7 PM | ESPN2 | #3 Baylor | #17 Oklahoma State | 11 | 10 | |
| 7 PM | ESPN+ | #6 West Virginia | TCU | 13 | 16 | |
| 7 PM | ESPN+ | #18 Texas Tech | Iowa State | 17 | 18 | #TexasTechBubble |
| 8 PM | ESPN+ | #13 Kansas | UTEP | 18 | 17 | |
| 9 PM | BTN | #5 Iowa | Nebraska | 16.5 | 22 | |
| 9 PM | ESPN | #16 Oklahoma | #15 Texas | 2 | 0 | #ppiupsetalert, Oklahoma -130 |
| 9 PM | ESPN2 | #24 Colorado | Arizona State | 10 | 17 | Colorado -10 |
| 11 AM | NBCSN | Richmond | Duquesne | 5.5 | 6 | #RichmondBubble |
| 7 PM | Cincinnati | Vanderbilt | 6.5 | 5 | ||
| 9:30 PM | FS1 | Utah State | Wyoming | 16.5 | 12 | Wyoming +16.5, #UtahStateBubble |