#ppiupsetalert record 1-0 (100%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 11:30 AM | ESPN2 | #18 Auburn (N) | Nebraska (N) | 13.5 | 16 | |
| 12 PM | BTN | #21 Ohio State | #22 Wisconsin | 4.5 | -1 | #ppiupsetalert, Wisconsin +4.5 |
| 12 PM | FS1 | Creighton | #24 BYU | -6.5 | -11 | BYU -6.5 |
| 12 PM | FOX | Georgetown | Syracuse | -3 | -5 | |
| 1:30 PM | ESPN2 | Oklahoma | #12 Arkansas | 0.5 | 3 | #ppiupsetalert, Oklahoma -0.5 |
| 2 PM | BTN | #19 Michigan State | Penn State | 10 | 17 | Michigan State -10 |
| 2 PM | FS1 | Providence | Central Connecticut State | 27 | 29 | |
| 2 PM | ESPNU | Colorado State (N) | Mississippi State (N) | 1 | 6 | Colorado State -1 |
| 2 PM | ACCN | Clemson (N) | Drake (N) | 2 | 1 | |
| 2:30 PM | FOX | Marquette | #4 UCLA | -5.5 | 3 | #ppiupsetalert, Marquette +205 |
| 3 PM | Washington State | South Dakota State | 5 | 7 | ||
| 3:15 PM | ESPN | #8 Kansas | Missouri | 23 | 22 | |
| 4 PM | ESPN2 | St. Bonaventure (N) | #15 Connecticut (N) | -4 | 4 | #ppiupsetalert, St. Bonaventure +4 |
| 4 PM | FS1 | Butler | Eastern Illinois | 22.5 | 21 | |
| 4 PM | San Jose State | Pacific | -1.5 | 11 | San Jose State +108 | |
| 4:30 PM | SECN | #13 Tennessee | UNC Greensboro | 18.5 | 14 | UNC Greensboro +19 |
| 5 PM | FOX | Illinois | #11 Arizona | -1 | -2 | #ppiupsetalert, Illinois +102 |
| 5 PM | Saint Louis | Boston College | 7 | 7 | ||
| 5 PM | PAC12 | Utah | Manhattan | 15.5 | 9 | Manhattan +15 |
| 5:15 PM | ESPN | Notre Dame | #10 Kentucky | -4 | -6 | |
| 6 PM | ESPN2 | Georgia Tech | #25 LSU | -8.5 | -8 | |
| 6:30 PM | SECN | TCU (N) | Texas A&M (N) | 1 | 1 | |
| 6:30 PM | FS1 | Michigan | Minnesota | 14.5 | 6 | Minnesota +14.5 |
| 7 PM | Wake Forest | South Carolina Upstate | 24.5 | 27 | ||
| 7 PM | Fresno State | UC Irvine | 2.5 | 4 | ||
| 8 PM | ACCN | North Carolina | Elon | 22.5 | 26 | |
| 8 PM | St. Thomas | Montana State | -4.5 | 0 | St. Thomas +4.5 | |
| 8:30 PM | FS1 | Xavier | Cincinnati | 7.5 | 7 | |
| 8:30 PM | SECN | Ole Miss (N) | Western Kentucky (N) | 5.5 | 4 | |
| 9 PM | Utah State | New Orleans | 19.5 | 20 | ||
| 9 PM | PAC12 | California | Santa Clara | 2 | -4 | Santa Clara +106 |
| 10 PM | ESPN2 | #9 Alabama | #14 Houston | 1.5 | 7 | Alabama -1.5 |
| 10 PM | Wyoming | Utah Valley | 7.5 | 3 |