#ppiupsetalert record: 2-5 (28.6%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6 PM | ACCN | Louisville | SE Louisiana | 21.5 | 25 | |
| 7 PM | ESPN+ | #18 Tennessee | South Carolina Upstate | 33.5 | 26 | South Carolina Upstate +33.5 |
| 7 PM | SECN | #19 LSU | Northwestern State | 32.5 | 29 | Northwestern State +32.5 |
| 7 PM | ACCNX | Wake Forest | VMI | 15.5 | 20 | Wake Forest -15.5 |
| 7 PM | ESPN2 | North Carolina | Furman | 11.5 | 13 | |
| 7 PM | ESPN+ | Clemson | Miami (OH) | 8.5 | 7 | |
| 8 PM | ACCN | #2 Duke | South Carolina State | 35.5 | 23 | South Carolina State +35.5 |
| 8 PM | ESPN+ | #14 Houston | Louisiana Lafayette | 21.5 | 18 | Louisiana Lafayette +21.5 |
| 8 PM | ESPN+ | #25 Texas Tech | Arkansas State | 24.5 | 10 | Arkansas State +24.5 |
| 8 PM | ESPN+ | UIC | DePaul | -10.5 | -14 | DePaul -10.5 |
| 8 PM | FS1 | Creighton | Arizona State | 7.5 | 7 | |
| 8 PM | ESPN+ | Mississippi State | Georgia State | 9.5 | 11 | |
| 8 PM | BTN | Minnesota | Texas A&M-CC | 15.5 | 14 | |
| 9 PM | ESPN | Memphis | #6 Alabama | -5 | -9 | Alabama -5 |
| 9 PM | SECN | #13 Auburn | North Alabama | 27.5 | 26 | |
| 9 PM | ESPNU | #17 Texas | Arkansas-Pine Bluff | 33.5 | 21 | Arkansas-Pine Bluff +33.5 |
| 10 PM | PAC12 | Oregon State | UC Davis | 6 | -5 | UC Davis +205 |