#ppiupsetalert record: 9-12 (42.9%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | SECN | South Carolina | #9 Auburn | -10.5 | -11 | |
| 7 PM | ESPN2 | #1 Baylor | Oklahoma | 13 | 9 | Oklahoma +13 |
| 7 PM | ESPN3 | Ball State | Kent State | -1.5 | 4 | Ball State +104 |
| 7 PM | ESPN+ | Kansas State | #14 Texas | -6 | 0 | #ppiupsetalert, Kansas State +202 |
| 7 PM | ESPN | #21 LSU | #16 Kentucky | 1.5 | 8 | #ppiupsetalert, LSU -122 |
| 7 PM | ACCNX | Wake Forest | Florida State | 1.5 | 5 | |
| 7 PM | ACCN | Virginia Tech | NC State | 10 | 8 | |
| 7 PM | ESPNU | Georgia | Texas A&M | -6 | -7 | |
| 7 PM | BTN | Rutgers | Michigan | -3.5 | -4 | |
| 7 PM | BTN | Minnesota | Illinois | -6.5 | 5 | Minnesota +220 |
| 8 PM | CBSSN | Butler | #24 Seton Hall | -3.5 | -1 | #ppiupsetalert, Butler +3.5 |
| 8:30 PM | SECN | Arkansas | Vanderbilt | 7.5 | 4 | |
| 9 PM | ACCN | #2 Duke | Georgia Tech | 18 | 14 | Georgia Tech +18 |
| 9 PM | ESPN2 | Oklahoma State | #6 Kansas | -6.5 | -7 | |
| 9 PM | FS1 | Marquette | #16 Providence | -2 | -5 | |
| 9 PM | #20 Colorado State | Air Force | 20 | 13 | Air Force +20 | |
| 9 PM | ACCNX | Clemson | Virginia | 4 | 9 | Clemson -4 |