#ppiupsetalert record: 10-15 (40.0%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | FS1 | St. John’s | DePaul | 5 | -1 | DePaul +168 |
| 7 PM | BTN | #10 Michigan State | Nebraska | 15.5 | 22 | Michigan State -15.5 |
| 7 PM | ESPN+ | South Florida | #12 Houston | -15 | -16 | |
| 7 PM | ESPN2 | Florida | #15 Alabama | 2 | -1 | #ppiupsetalert, Florida -132 |
| 7 PM | SECN | #18 Tennessee | Ole Miss | 17.5 | 12 | Ole Miss +17.5 |
| 7 PM | ESPNU | Louisville | Pittsburgh | 12.5 | 17 | Louisville -12.5 |
| 8 PM | ACCN | Miami (FL) | Syracuse | 2 | 8 | Miami (FL) -2 |
| 8:30 PM | FS1 | #19 Villanova | Creighton | 10.5 | 9 | |
| 9 PM | ESPNU | #11 Iowa State | #25 Texas Tech | 4 | 9 | Iowa State -4 |
| 9 PM | ESPN2 | Notre Dame | North Carolina | -2 | -6 | North Carolina -2 |
| 9 PM | BTN | Northwestern | Penn State | 7.5 | 3 | Penn State +7.5 |