#ppiupsetalerecord: 13-20 (39.4%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | FS1 | #17 Xavier | #14 Villanova | -1 | 1 | #ppiupsetalert, Xavier -110 |
| 7 PM | ACCN | Wake Forest | #8 Duke | -5 | 4 | #ppiupsetalert, Wake Forest +172 |
| 7 PM | BTN | #10 Michigan State | Minnesota | 12.5 | 11 | |
| 7 PM | ESPN2 | Florida | #12 LSU | 1 | -5 | #ppiupsetalert, Florida -115 |
| 7 PM | ACCNX | Notre Dame | Clemson | 3 | 0 | |
| 7 PM | SECN | Mississippi State | Georgia | 15.5 | 17 | |
| 8 PM | CBSSN | Colorado State | Utah State | 5 | 7 | |
| 8:30 PM | FS1 | Connecticut | St. John’s | 11.5 | 9 | |
| 9 PM | ACCN | Louisville | NC State | 6 | 9 | |
| 9 PM | ESPN2 | Virginia | Virginia Tech | 1.5 | 5 | Virginia -1.5 |
| 9 PM | ACCNX | Boston College | Georgia Tech | 2 | 2 | |
| 9 PM | ESPNU | Kansas State | TCU | 3 | 0 | |
| 9 PM | SECN | Arkansas | Missouri | 14 | 7 | Missouri +14 |
| 9 PM | BTN | Northwestern | Maryland | 4 | 3 | |
| 10 PM | PAC12 | Washington | California | -1 | 0 | |
| 10:30 PM | FS1 | Nevada | Boise State | -1.5 | -2 |