#ppiupsetrecord: 14-24 (36.8%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6 PM | CBSSN | Ball State | Buffalo | -6.5 | -2 | Ball State +6.5 |
| 6:30 PM | FS1 | #7 Purdue | Nebraska | 20 | 20 | |
| 9 PM | FS1 | #25 Illinois | Michigan | 9.5 | 12 | |
| 11 PM | FS1 | UNLV | Fresno State | 1 | -1 |
PPI Projections: January 14, 2022
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