#ppiupsetalertrecord: 32-50 (39.0%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | SECN | Florida | Georgia | 14.5 | 18 | |
| 7 PM | ESPN | SMU | #6 Houston | -7 | -3 | #ppiupsetalert, SMU +7 |
| 7 PM | BTN | Rutgers | #16 Ohio State | -3 | 0 | #ppiupsetalert, Rutgers +3 |
| 7 PM | FS1 | Seton Hall | #25 Xavier | 3.5 | 1 | #ppiupsetalert, Seton Hall -156 |
| 7 PM | ACCN | NC State | Wake Forest | -3 | -6 | |
| 7 PM | ACCNX | Miami (FL) | Georgia Tech | 9 | 13 | Miami (FL) -9 |
| 7 PM | ESPNU | Notre Dame | Louisville | 7 | 11 | Notre Dame -7 |
| 8 PM | ESPN+ | Kansas State | #10 Baylor | -7 | -6 | |
| 8:30 PM | SECN | Ole Miss | Alabama | -5.5 | -2 | |
| 9 PM | ESPNU | Oklahoma | #9 Texas Tech | -3 | -1 | #ppiupsetalert, Oklahoma +3 |
| 9 PM | ESPN2 | Mississippi State | #19 Tennessee | -1.5 | -3 | #ppiupsetalert, Mississippi St +1.5 |
| 9 PM | FS1 | DePaul | Georgetown | 8 | 12 | DePaul -8 |
| 9 PM | ACCN | Florida State | Pittsburgh | 10.5 | 14 | Florida State -10.5 |
| 9 PM | BTN | Nebraska | Minnesota | -1.5 | -4 | |
| 11 PM | ESPNU | Oregon State | California | 1 | -3 | California +100 |