#ppiupsetalertrecord: 0-0 (0.0%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12:30 PM | FS1 | #5 Connecticut | Long Island | 40 | 39 | |
| 2 PM | ESPN+ | Ball State | Evansville | 9.5 | 11 | |
| 6 PM | ESPN+ | Montana State | Omaha | 11.5 | 7 | |
| 12 PM | BTN | #17 Illinois | Penn State | 10.5 | 7 | |
| 1 PM | LHN | #2 Texas | Arkansas-Pine Bluff | 36.5 | 19 | Arkansas-Pine Bluff +36.5 |
| 1 PM | ESPN2 | #9 Arkansas (N) | Oklahoma (N) | 3.5 | 6 | |
| 1 PM | SECN | #16 Kentucky | Yale | 16.5 | 4 | |
| 1 PM | ACCN | Florida State | Louisville | 9.5 | 1 | Louisville +9.5 |
| 1 PM | ABC | Syracuse | Georgetown | 8.5 | 11 | |
| 2 PM | ACCNX | Miami (FL) | NC State | 4.5 | 10 | Miami (FL) -4.5 |
| 2 PM | LSU (N) | Wake Forest (N) | -1.5 | 4 | LSU +1.5 | |
| 2:15 PM | BTN | Nebraska | #4 Purdue | -9 | -10 | |
| 2:30 PM | FS1 | Providence | Albany | 22 | 23 | |
| 3 PM | ABC | #1 Houston | #8 Alabama | 8 | 6 | |
| 3 PM | PAC12 | #19 UCLA | Denver | 26.5 | 17 | Denver +26.5 |
| 3 PM | ESPN+ | #22 San Diego State (N) | Saint Mary’s (N) | 1 | 1 | |
| 3 PM | ESPN2 | Xavier (N) | Cincinnati (N) | 4 | 3 | |
| 3 PM | SECN | Ole Miss | Valparaiso | 15 | 16 | |
| 3:15 PM | ESPN | North Carolina | Georgia Tech | 13 | 8 | |
| 3:30 PM | ACCN | Pittsburgh | Sacred Heart | 17.5 | 15 | |
| 4:30 PM | FS1 | UNLV | Washington State | 1.5 | 12 | UNLV -1.5 |
| 4:30 PM | BTN | Michigan State | Brown | 16 | 16 | |
| 5 PM | ESPN2 | #11 Auburn (N) | Memphis (N) | 1.5 | 4 | |
| 5 PM | PAC12 | California | Butler | -8.5 | -16 | Butler -8.5 |
| 5 PM | FOX | Villanova (N) | Boston College (N) | 9.5 | 2 | Boston College +9.5 |
| 5:15 PM | ESPN | Missouri | #6 Kansas | -3 | -4 | #ppiupsetalert, Missouri +134 |
| 5:30 PM | ACCN | #15 Duke | Maryland-Eastern Shore | 31.5 | 29 | |
| 6 PM | FS2 | St. John’s | New Hampshire | 22.5 | 24 | |
| 6 PM | ESPN+ | West Virginia | UAB | 6.5 | 13 | West Virginia -6.5 |
| 6:30 PM | FS1 | DePaul | UTEP | 6.5 | 8 | |
| 7 PM | PAC12 | Oregon | Nevada | 8.5 | 0 | Nevada +8.5 |
| 7:30 PM | FOX | #10 Arizona (N) | #14 Indiana (N) | 1.5 | 0 | |
| 7:30 PM | ACCN | Clemson (N) | Loyola (CHI) (N) | 4.5 | 16 | Clemson -4.5 |
| 10 PM | FS1 | #21 Creighton (N) | BYU (N) | 9.5 | 7 | |
| 10 PM | ESPN2 | SMU | #24 TCU | -12 | -11 |