#ppiupsetalertrecord: 8-7 (53.3%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | FS1 | #2 Connecticut | Villanova | 12 | 20 | Connecticut -12 |
| 5 PM | SECN | Ole Miss | #7 Tennessee | -7.5 | -3 | #ppiupsetalert, Ole Miss +7.5 |
| 5 PM | ESPN+ | #18 TCU | Central Arkansas | 25.5 | 18 | Central Arkansas +25.5 |
| 6 PM | ACCN | #13 Virginia | Albany | 27.5 | 28 | |
| 7 PM | SECN | Missouri | #19 Kentucky | -3.5 | 6 | #ppiupsetalert, Missouri +128 |
| 7 PM | ESPN2 | #20 Auburn | Florida | 5.5 | 17 | Auburn -5.5 |
| 8 PM | ESPN+ | #12 Baylor | Nicholls State | 20.5 | 12 | Nicholls State +20.5 |
| 9 PM | ESPNU | Tulsa | #3 Houston | -20.5 | -17 | |
| 9 PM | SECN | #21 Mississippi State | #8 Alabama | -1 | -1 | #ppiupsetalert, Mississippi State -108 |
| 9 PM | ESPN2 | LSU | #9 Arkansas | -4.5 | -3 | #ppiupsetalert, LSU +4.5 |
| 9 PM | FS1 | St. John’s | #22 Xavier | -1.5 | 1 | #ppiupsetalert, St. John’s +100 |
| 9 PM | CBSSN | #22 New Mexico | Colorado State | 5.5 | 17 | New Mexico -5.5 |