#ppiupsetalertrecord 16-13 (55.2%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 7 PM | FS1 | #24 Ohio State | #1 Purdue | 1.5 | -5 | Purdue +104 |
| 7 PM | ESPN2 | #2 Houston | SMU | 19.5 | 26 | Houston -19.5 |
| 9 PM | FS1 | Iowa | #15 Indiana | 1.5 | -1 | #ppiupsetalert, Iowa -118 |
| 9:30 PM | ESPN | #10 UCLA | USC | 11.5 | 13 | |
| 11 PM | FS1 | #5 Arizona | Washington | 18.5 | 16 | |
| 11 PM | ESPN2 | San Francisco | #9 Gonzaga | -9.5 | -5 | #ppiupsetalert, San Francisco +9.5 |
| 8 PM | ESPN+ | Northern Colorado | Montana State | -2.5 | 2 | Northern Colorado +118 |
| 6:30 PM | BTN | Rutgers | Maryland | 4.5 | -1 | Maryland +172 |
| 8 PM | PAC12 | Arizona State | Washington State | 4.5 | 11 | Arizona State -4 |
| 9 PM | ESPN2 | Colorado | Oregon | 2.5 | 4 | |
| 10 PM | PAC12 | Utah | Oregon State | 13.5 | 12 |