#ppiupsetalertrecord 17-14 (54.8%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FOX | #4 Connecticut | Creighton | 7.5 | 16 | Connecticut -7.5 |
| 12 PM | ESPNU | Oklahoma State | #6 Texas | -1.5 | 1 | #ppiupsetalert, Oklahoma State +108 |
| 12 PM | CBS | #20 Missouri | Vanderbilt | 8.5 | 10 | |
| 1 PM | ESPN | #7 Alabama | Kentucky | 5.5 | 13 | Alabama -5.5 |
| 1 PM | ACCN | Boston College | #16 Duke | -8.5 | -9 | |
| 1:30 PM | ESPN2 | Illinois | #14 Wisconsin | 5.5 | -4 | |
| 2 PM | ESPNU | #17 TCU | #25 Iowa State | 6.5 | 5 | |
| 3:30 PM | SECN | South Carolina | #8 Tennessee | -17.5 | -11 | South Carolina +17.5 |
| 4:30 PM | FS1 | Villanova | #18 Xavier | 0.5 | -7 | Xavier -104 |
| 5 PM | PAC12 | #5 Arizona | Washington State | 12.5 | 20 | Arizona -12.5 |
| 5 PM | ACCN | #11 Virginia | Syracuse | 11 | 10 | |
| 5 PM | CBSSN | #23 Charleston | Delaware | 11.5 | 19 | Charleston -11.5 |
| 6 PM | ESPN+ | West Virginia | #3 Kansas | -2.5 | -7 | Kansas -2.5 |
| 6 PM | ESPN+ | #19 Baylor | Kansas State | 6.5 | -1 | #ppiupsetalert, Kansas State +220 |
| 8:30 PM | SECN | #22 Auburn | #13 Arkansas | 2.5 | 8 | #ppiupsetalert, Auburn -2.5 |
| 9:30 PM | CBSSN | #21 New Mexico | UNLV | 4.5 | 10 | New Mexico -4.5 |
| 10 PM | Santa Clara | #9 Gonzaga | -7.5 | 0 | #ppiupsetalert, Santa Clara +270 | |
| 4 PM | ESPN+ | Northern Arizona | Montana State | -5.5 | -6 | |
| 11:30 AM | ESPN2 | North Carolina | Notre Dame | 12.5 | 15 | |
| 12 PM | FS1 | Providence | St. John’s | 6.5 | 7 | |
| 12 PM | CBSSN | Minnesota | Nebraska | -3.5 | -5 | |
| 1 PM | ACCNX | Florida State | Georgia Tech | 2.5 | -5 | Georgia Tech +116 |
| 1 PM | SECN | Florida | Georgia | 7.5 | 0 | Georgia +255 |
| 2 PM | FS1 | Marquette | Georgetown | 19.5 | 23 | |
| 2 PM | CBS | Mississippi State | Ole Miss | 5.5 | 8 | |
| 2:30 PM | FOX | Michigan State | Michigan | 3.5 | 9 | Michigan State -3.5 |
| 3 PM | ACCN | Louisville | Wake Forest | -9.5 | -12 | |
| 4 PM | ESPN2 | Pittsburgh | Clemson | 2.5 | -1 | |
| 6 PM | SECN | Texas A&M | LSU | 3.5 | 3 | |
| 7 PM | ESPN+ | Texas Tech | Oklahoma | 4.5 | 2 | |
| 7 PM | PAC12 | Utah | Oregon | 5.5 | 4 | |
| 7:30 PM | ACCNX | Virginia Tech | NC State | 5.5 | 1 | NC State +5.5 |
| 8:30 PM | FS1 | Seton Hall | Butler | 4.5 | 5 | |
| 9:30 PM | CBSSN | Colorado | Oregon State | 13.5 | 14 |