#ppiupsetalertrecord 42-28 (60.0%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | FS1 | #19 Connecticut | #13 Xavier | 6.5 | 7 | #ppiupsetalert, Connecticut -285 |
| 7 PM | ESPN+ | UCF | #3 Houston | -10.5 | -7 | |
| 7 PM | SECN | #4 Tennessee | Georgia | 16.5 | 13 | |
| 8:30 PM | FS1 | #23 Providence | Butler | 10.5 | 11 | |
| 9 PM | SECN | #2 Alabama | Mississippi State | 12.5 | 18 | Alabama -12.5 |
| 9 PM | ESPN2 | #15 Auburn | Texas A&M | 4.5 | 12 | Auburn -4.5 |
| 7 PM | ESPNU | Texas Tech | West Virginia | 3.5 | 0 | |
| 7 PM | ACCN | Pittsburgh | Wake Forest | 2.5 | 2 | |
| 7 PM | BTN | Maryland | Wisconsin | 4.5 | 5 | |
| 7 PM | FS2 | Nebraska | Northwestern | -2.5 | 1 | |
| 9 PM | ACCN | Boston College | Louisville | 9.5 | 11 | |
| 9 PM | CBSSN | Creighton | St. John’s | 10.5 | 7 | |
| 9 PM | BTN | Minnesota | Indiana | -9.5 | -8 | |
| 10 PM | PAC12 | Stanford | Chicago State | 17.5 | 14 | |
| 11 PM | CBSSN | San Diego State | Utah State | 6.5 | 6 |