#ppiupsetalertrecord 60-38 (61.2%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | ESPN2 | #5 Texas | West Virginia | 6.5 | 7 | |
| 12 PM | FS1 | Georgetown | #10 Marquette | -10.5 | -14 | Marquette -10.5 |
| 12 PM | FOX | St. John’s | #20 Providence | -4.5 | -5 | |
| 12 PM | ACCNX | Boston College | #22 NC State | -6.5 | -6 | |
| 1 PM | CBS | Oklahoma | #9 Kansas | -3.5 | -6 | |
| 2 PM | ESPN | Auburn | #3 Alabama | -2.5 | -1 | #ppiupsetalert, Auburn +126 |
| 2 PM | FS1 | Illinois | #24 Rutgers | 5.5 | 9 | Illinois -260 |
| 4 PM | ESPN | #8 Virginia | Duke | 6.5 | 6 | |
| 4 PM | ESPN2 | #17 TCU | #14 Baylor | -2.5 | -4 | #ppiupsetalert, TCU +108 |
| 4 PM | FOX | #25 San Diego State | UNLV | 8.5 | 15 | San Diego State -8.5 |
| 6 PM | SECN | #6 Tennessee | Missouri | 12.5 | 10 | |
| 6 PM | ESPN2 | #11 Iowa State | Oklahoma State | 6.5 | 5 | |
| 6 PM | CBSSN | Portland | #15 Saint Mary’s | -11.5 | -11 | |
| 6 PM | ESPN | Michigan | #18 Indiana | 1.5 | 3 | #ppiupsetalert, Indiana -142 |
| 7 PM | ESPN+ | Texas Tech | #12 Kansas State | -1.5 | -7 | Kansas State -1.5 |
| 7 PM | ACCN | #19 Miami (FL) | Louisville | 19.5 | 26 | Miami (FL) -19.5 |
| 8 PM | ESPN2 | Stanford | #4 Arizona | -7.5 | -14 | Arizona -7.5 |
| 10 PM | ESPN | Oregon | #7 UCLA | -2.5 | -3 | #ppiupsetalert, Oregon +116 |
| 10 PM | ESPN2 | #16 Gonzaga | BYU | 12.5 | 15 | |
| 2 PM | ESPN3 | Ball State | Bowling Green | 8.5 | 12 | Ball State -8.5 |
| 8 PM | ESPN+ | Idaho State | Montana State | -6.5 | -6 | |
| 12 PM | ESPNU | Florida State | Pittsburgh | -4.5 | -6 | |
| 12 PM | BTN | Maryland | Penn State | 8.5 | 8 | |
| 12 PM | ESPN | Georgia | Kentucky | -7.5 | -1 | Georgia +7.5 |
| 1 PM | SECN | Ole Miss | South Carolina | 8.5 | 8 | |
| 2 PM | ACCNX | Notre Dame | Virginia Tech | -5.5 | -4 | |
| 2 PM | ESPN2 | North Carolina | Clemson | 6.5 | 2 | Clemson +6.5 |
| 3:30 PM | SECN | Florida | Vanderbilt | 8.5 | 6 | |
| 4 PM | BTN | Nebraska | Wisconsin | -3.5 | -4 | |
| 5 PM | ACCN | Wake Forest | Georgia Tech | 12.5 | 13 | |
| 6 PM | PAC12 | Oregon State | USC | -9.5 | -9 | |
| 6 PM | ESPNU | Arkansas | Mississippi State | 6.5 | 9 | |
| 8 PM | PAC12 | California | Arizona State | -9.5 | -9 | |
| 8 PM | FS1 | Villanova | Seton Hall | 5.5 | 1 | Seton Hall +5.5 |
| 8 PM | CBSSN | Boise State | Wyoming | 13.5 | 19 | Boise State -13.5 |
| 8:30 PM | SECN | LSU | Texas A&M | -6.5 | -6 | |
| 10 PM | FS1 | Utah | Colorado | 3.5 | 4 | |
| 10 PM | CBSSN | San Jose State | Utah State | -6.5 | -4 | |
| 10:30 PM | PAC12 | Washington State | Washington | 6.5 | 2 | Washington +6.5 |