| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | TBS | #3 Kansas State | #7 Michigan State | -1.5 | 2 | NCAA Sweet 16 East – Kansas State +106 |
| 7:15 PM | CBS | #4 Connecticut | #8 Arkansas | 4 | 8 | NCAA Sweet 16 West – UConn -4 |
| 9 PM | TBS | #4 Tennessee | #9 Florida Atlantic | 5 | -6 | NCAA Sweet 16 East – Florida Atlantic +190 |
| 9:45 PM | CBS | #2 UCLA | #3 Gonzaga | 1.5 | -8 | NCAA Sweet 16 West – Gonzaga -102 |
PPI Projections: March 23, 2023
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