| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | TBS | #1 Alabama | #5 San Diego State | 6.5 | 2 | NCAA Sweet 16 South – San Diego St +6.5 |
| 7:15 PM | CBS | #1 Houston | #5 Miami (FL) | 7.5 | 8 | NCAA Sweet 16 Midwest |
| 9 PM | TBS | #6 Creighton | #15 Princeton | 10.5 | 6 | NCAA Sweet 16 South – Princeton +10.5 |
| 9:45 PM | CBS | #2 Texas | #3 Xavier | 4.5 | 7 | NCAA Sweet 16 Midwest |
PPI Projections: March 24, 2023
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