#ppiupsetalertrecord: 0-0 (.000)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FS2 | #5 Connecticut | Arkansas-Pine Bluff | 37 | 24 | Arkansas-Pine Bluff +37 |
| 12 PM | ESPN2 | #16 Kentucky | Pennsylvania | 13.5 | 13 | |
| 12 PM | CBS | #17 Tennessee | #20 Illinois | 6.5 | 3 | #ppiupsetalert, Illinois +235 |
| 1:30 PM | FOX | #4 Purdue | Alabama | 5.5 | 11 | @ Toronto, ON, Purdue -5.5 |
| 2 PM | FS2 | #10 Creighton | Central Michigan | 30.5 | 19 | Central Michigan +30.5 |
| 2:15 PM | CW | #22 Duke | Charlotte | 15.5 | 3 | #ppiupsetalert, Charlotte +15.5 |
| 3 PM | LHN | #12 Texas | Houston Christian | 32.5 | 18 | Houston Christian +32.5 |
| 3:15 PM | ESPN | #1 Arizona | #23 Wisconsin | 9.5 | 6 | Wisconsin +9.5 |
| 4 PM | ESPN+ | #3 Houston | Jackson State | 31.5 | 28 | Jackson State +31.5 |
| 4 PM | ESPN2 | #19 Oklahoma | Arkansas | 3.5 | 12 | Oklahoma -3.5 |
| 4 PM | FS1 | TCU | #24 Clemson | -1.5 | -12 | @ Toronto, ON, Clemson -110 |
| 5:15 PM | ESPN | #2 Kansas | Missouri | 13.5 | 9 | Missouri +13.5 |
| 6:30 PM | CBSSN | #13 Colorado State | Saint Mary’s | 5.5 | 17 | Colorado State -5.5 |
| 7 PM | PAC12 | Utah | #14 BYU | -3.5 | -2 | #ppiupsetalert, Utah +146 |
| 7 PM | ESPN+ | Old Dominion | #18 James Madison | -6.5 | -15 | James Madison -6.5 |
| 9 PM | FOX | #8 Marquette | Notre Dame | 20.5 | 19 | |
| 10:30 PM | FS1 | #25 San Diego State | UC Irvine | 9.5 | 3 | #ppiupsetalert, UC Irvine +360 |
| 11 PM | ESPN2 | Washington | #7 Gonzaga | -4.5 | -1 | #ppiupsetalert, Washington +152 |
| 1:30 PM | SECN | LSU | Kansas State | 2.5 | -4 | Kansas State +118 |
| 4 PM | ESPN+ | West Virginia | Drexel | 4.5 | -3 | Drexel +152 |
| 6:30 PM | FS1 | Xavier | Cincinnati | -1.5 | -4 | |
| 11:30 AM | SECN | Mississippi State | Tulane | 7.5 | 4 | @ Atlanta, GA, Tulane +7.5 |
| 12 PM | ESPNU | East Carolina | South Carolina | -5.5 | -8 | |
| 2 PM | ESPN2 | Indiana | Auburn | -7.5 | 1 | @ Atlanta, GA, Indiana +245 |
| 4 PM | SECN | Florida | Richmond | 10.5 | 3 | @ Sunrise, FL, Richmond +10.5 |
| 11:30 AM | FOX | Georgetown | Syracuse | -1.5 | -4 | |
| 12 PM | CW | Virginia Tech | Valparaiso | 21.5 | 21 | |
| 1:30 PM | ACCN | South Florida | Florida State | -7.5 | -9 | @ Sunrise, FL |
| 2 PM | FS1 | DePaul | Louisville | 1.5 | -6 | Louisville -106 |
| 4 PM | ACCN | Georgia Tech | Alabama A&M | 19.5 | 16 | Alabama A&M +19.5 |
| 6 PM | ACCN | Pittsburgh | Canisius | 17.5 | 10 | Canisius +17.5 |
| 8 PM | ACCN | Wake Forest | NJIT | 24.5 | 18 | NJIT +24.5 |
| 12 PM | FS1 | Butler | California | 9.5 | 16 | Butler -9.5 |
| 5 PM | PAC12 | Oregon State | Utah Valley | 2.5 | 2 | |
| 7 PM | FOX | Villanova | UCLA | 3.5 | 13 | Villanova -3.5 |
| 9 PM | PAC12 | Oregon | UTEP | 12.5 | 6 | UTEP +12.5 |
| 10:30 PM | CBSSN | UC San Diego | Arizona State | -8.5 | -4 | UC San Diego +8.5 |
| 12 PM | BTN | Minnesota | Florida Gulf Coast | 9.5 | 7 | |
| 6 PM | BTN | Penn State | Ohio State | -5.5 | -12 | Ohio State -5.5 |
| 8:30 PM | FS1 | Seton Hall | Rutgers | 3.5 | -1 | @ Newark, NJ, Rutgers +146 |
| 4 PM | Wyoming | Stephen F. Austin | -1.5 | 0 | ||
| 5 PM | Santa Clara | New Mexico | -9.5 | -8 | @ Henderson, NV | |
| 5 PM | San Jose State | New Orleans | 10.5 | 6 | New Orleans +10.5 | |
| 6 PM | Air Force | Eastern Washington | 7.5 | 9 | ||
| 7 PM | Fresno State | Pacific | 14.5 | 16 | ||
| 7:30 PM | Drake | Nevada | -4.5 | -2 | @ Henderson, NV | |
| 10 PM | UNLV | Loyola Marymount | 2.5 | -5 | @ Henderson, NV, Loyola Marymount +128 | |
| 12 PM | ESPN+ | Massachusetts | Umass Lowell | 5.5 | 2 | UMass Lowell +5.5 |
| 12:30 PM | USA | Dayton | Troy | 13.5 | 15 | |
| 2 PM | ESPN+ | Lafayette | La Salle | -4.5 | -17 | La Salle -4.5 |
| 2 PM | ESPN+ | Davidson | Miami (OH) | 13.5 | 13 | |
| 3 PM | ESPN+ | Saint Louis | Hofstra | -3.5 | -5 | |
| 4 PM | ESPN+ | St. Bonaventure | Siena | 22.5 | 24 | |
| 6 PM | ESPN+ | George Washington | Coppin State | 20.5 | 26 | George Washington -20.5 |