#ppiupsetalertrecord: 5-6 (.455)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 7 PM | BTN | #1 Purdue | Eastern Kentucky | 28.5 | 36 | Purdue -28.5 |
| 7 PM | SECN | #8 Kentucky | Illinois State | 19.5 | 15 | Illinois State +19.5 |
| 7 PM | ACCNX | #18 Clemson | Radford | 15.5 | 18 | |
| 8 PM | ACCN | #9 North Carolina | Charleston Southern | 32.5 | 30 | |
| 8 PM | LHN | #21 Texas | UNC Greensboro | 15.5 | 8 | UNC Greensboro +15.5 |
| 9 PM | BTN | #11 Illinois | Fairleigh Dickinson | 26.5 | 15 | Fairleigh Dickinson +26.5 |
| 9 PM | ESPN2 | #13 Gonzaga | San Diego State | 6.5 | 4 | |
| 10:30 PM | PAC12 | California | #4 Arizona | -13.5 | -15 | |
| 2 PM | Penn State | Rider | 14.5 | 9 | Rider +14.5 | |
| 6 PM | ACCN | Miami (FL) | North Florida | 20.5 | 22 | |
| 6 PM | Indiana | Kennesaw State | 11.5 | 11 | ||
| 7 PM | Iowa | Northern Illinois | 17.5 | 8 | Northern Illinois +17.5 | |
| 7 PM | ESPN+ | Cincinnati | Evansville | 17.5 | 8 | Evansville +17.5 |
| 7 PM | BTN | Michigan | McNeese State | 10.5 | 4 | McNeese State +10.5 |
| 7 PM | Peacock | Minnesota | Maine | 13.5 | 10 | Maine +13.5 |
| 7 PM | ESPN+ | UCF | Bethune-Cookman | 23.5 | 25 | |
| 7:30 PM | Nebraska | South Carolina State | 25.5 | 23 | ||
| 8 PM | ESPN+ | LSU | Northwestern State | 24.5 | 22 | |
| 8 PM | Peacock | Northwestern | Jackson State | 18.5 | 15 | Jackson State +18.5 |
| 8:30 PM | PAC12 | Utah | Washington State | 7.5 | 14 | Utah -7.5 |
| 9 PM | ESPNU | Colorado | Washington | 9.5 | 3 | Washington +9.5 |