#ppiupsetalertrecord: 22-28 (.440)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 7:30 PM | ESPN | Alabama | #8 Auburn | 3.5 | -3 | #ppiupsetalert, Alabama -166 |
| 8 PM | ESPN+ | Rice | #22 Florida Atlantic | -11.5 | -12 | |
| 9 PM | BTN | Northwestern | #10 Illinois | -2.5 | -2 | #ppiupsetalert, Northwestern +128 |
| 9 PM | CBSSN | DePaul | #14 Marquette | -17.5 | -14 | DePaul +17.5 |
| 9 PM | ESPN2 | #23 Iowa State | Kansas State | 7.5 | 2 | #ppiupsetalert, Kansas State +285 |
| 10:30 PM | FS1 | Nevada | #24 Colorado State | 3.5 | 2 | #ppiupsetalert, Nevada -156 |
| 11 PM | CBSSN | San Jose State | #25 New Mexico | -8.5 | -13 | New Mexico -8.5 |
| 6:30 PM | FS1 | Seton Hall | Providence | 4.5 | 12 | Seton Hall -4.5 |
| 6:30 PM | SECN | Georgia | LSU | 4.5 | 7 | |
| 7 PM | ESPN2 | Notre Dame | Miami (FL) | -4.5 | -1 | Notre Dame +4.5 |
| 7 PM | ACCN | Virginia | NC State | 5.5 | 5 | |
| 7 PM | BTN | Iowa | Maryland | 5.5 | 3 | |
| 8:30 PM | FS1 | St. John’s | Villanova | 3.5 | 1 | |
| 8:30 PM | SECN | Florida | Mississippi State | 3.5 | 4 | |
| 9 PM | ESPNU | Ole Miss | Arkansas | 5.5 | 10 | Ole Miss -5.5 |
| 10 PM | PAC12 | Washington State | Utah | 1.5 | 1 | |
| 11 PM | ESPNU | Washington | Colorado | -2.5 | 0 |