#ppiupsetalertrecord: 49-55 (.471)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 8:30 PM | FS1 | #15 Creighton | #1 Connecticut | -2.5 | -2 | #ppiupsetalert, Creighton +125 |
| 7 PM | SECN | Missouri | #5 Tennessee | -11.5 | -17 | Tennessee -11.5 |
| 9 PM | ESPN | #25 BYU | #11 Baylor | 4.5 | 6 | #ppiupsetalert, BYU -194 |
| 9 PM | CBSSN | Utah State | #19 San Diego State | 1.5 | 7 | #ppiupsetalert, Utah State -128 |
| 9 PM | ESPN2 | #23 Texas Tech | TCU | 5.5 | 3 | #ppiupsetalert, TCU +176 |
| 11 PM | ESPN2 | #18 Saint Mary’s | San Francisco | 7.5 | 5 | |
| 6:30 PM | FS1 | Villanova | Butler | 6.5 | 5 | |
| 7 PM | ESPN2 | NC State | Syracuse | 5.5 | 4 | |
| 7 PM | ACCN | Florida State | Boston College | 3.5 | 4 | |
| 7 PM | ESPNU | West Virginia | UCF | -2.5 | -5 | |
| 7 PM | Michigan State | Iowa | 9.5 | 9 | ||
| 7 PM | ESPN | Texas A&M | Arkansas | 11.5 | 11 | |
| 8 PM | ESPN+ | Northern Illinois | Ball State | 1.5 | 3 | |
| 9 PM | ACCN | Wake Forest | Pittsburgh | 5.5 | 2 | Pittsburgh +5.5 |
| 9 PM | Peacock | Wisconsin | Maryland | 7.5 | 10 | |
| 10:30 PM | FS1 | Boise State | San Jose State | 15.5 | 19 | Boise State -15.5 |
| 11 PM | CBSSN | Nevada | Wyoming | 13.5 | 12 |