#ppiupsetalert record: 20-19 (.513)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | FS1 | Georgetown | #20 St. John’s | -5.5 | -7 | |
| 7 PM | ESPN | #6 Tennessee | #9 Kentucky | 10.5 | 14 | Tennessee -10.5 |
| 7 PM | ACCN | #25 Louisville | Wake Forest | 9.5 | 9 | |
| 7 PM | Peacock | Seton Hall | Providence | -3.5 | -5 | |
| 7 PM | SECN | Georgia | South Carolina | 7.5 | 7 | |
| 7 PM | ESPN+ | Ball State | Western Michigan | 4.5 | 9 | Ball State -4.5 |
| 8 PM | Peacock | #8 Michigan State | Minnesota | 14.5 | 19 | Michigan State -14.5 |
| 8 PM | ESPN+ | #12 Kansas | UCF | 12.5 | 6 | UCF +12.5 |
| 8 PM | CBSSN | Saint Louis | VCU | -5.5 | -7 | |
| 8 PM | ESPN+ | St. Bonaventure | Dayton | -1.5 | 0 | |
| 8 PM | ESPN+ | Valparaiso | Southern Illinois | 1.5 | 2 | |
| 8:30 PM | FS1 | Butler | #10 Marquette | -8.5 | -12 | Marquette -8.5 |
| 8:30 PM | Wyoming | Fresno State | 8.5 | 9 | ||
| 9 PM | SECN | #13 Texas A&M | Oklahoma | 8.5 | 8 | |
| 9 PM | ESPN2 | BYU | Baylor | 3.5 | 3 | |
| 9 PM | ESPN+ | Colorado | Arizona State | 3.5 | 0 | Arizona State +134 |
| 9 PM | ESPN | Pittsburgh | North Carolina | 2.5 | 5 | |
| 9 PM | ACCN | Notre Dame | Georgia Tech | 7.5 | 8 | |
| 9 PM | Colorado State | Air Force | 16.5 | 24 | Colorado State -16.5 | |
| 10 PM | CBSSN | Utah | Cincinnati | -1.5 | 3 | Utah -110 |
| 10:40 PM | FS1 | San Diego State | San Jose State | 14.5 | 17 | |
| 11 PM | ESPN2 | Gonzaga | Oregon State | 15.5 | 9 | Oregon State +15.5 |