#ppiupsetalert record: 33-33 (.500)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | ESPN | Wichita State | #14 Memphis | -8.5 | -12 | Memphis -8.5 |
| 1 PM | CBS | Ohio State | #20 Michigan | 1.5 | -2 | #ppiupsetalert, Ohio State -128 |
| 2 PM | ESPN2 | Drake | Bradley | 5.5 | 7 | |
| 3 PM | FS1 | #9 St. John’s | #24 Creighton | 5.5 | 5 | |
| 3 PM | ESPN+ | UIC | Missouri State | 5.5 | 11 | UIC -5.5 |
| 3 PM | BTN | Northwestern | Nebraska | -1.5 | -7 | Nebraska -1.5 |
| 4 PM | CBSSN | New Mexico | Utah State | 4.5 | 3 | |
| 5 PM | FS1 | #25 Maryland | Iowa | 10.5 | 14 | Maryland -10.5 |
| 7 PM | ESPN+ | Murray State | Northern Iowa | 1.5 | 0 | |
| 7 PM | FS1 | Oregon | Rutgers | 7.5 | 11 | Oregon -7.5 |
| 8 PM | ACCN | Notre Dame | Louisville | -7.5 | -12 | Louisville -7.5 |
| 8 PM | ESPN+ | Evansville | Valparaiso | 1.5 | 4 |