#ppiupsetalert record: 43-40 (.518)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 1 PM | ESPN+ | Southern Illinois | Indiana State | 5.5 | -1 | MVC Rd 1, Indiana St +142 |
| 3:30 PM | ESPN+ | Illinois State | Missouri State | 5.5 | 7 | MVC Rd 1, Illinois St -5.5 |
| 5:30 PM | ESPN+ | Pacific | San Diego | 1.5 | 4 | West Coast Rd 1 |
| 6 PM | ESPN+ | Georgia State | Georgia Southern | -2.5 | -2 | Sun Belt Rd 3 |
| 7 PM | Omaha | Kansas City | 3.5 | 7 | Summit QF | |
| 7 PM | ESPN+ | Bucknell | Loyola (MD) | 8.5 | 10 | Patriot QF |
| 7 PM | ESPN+ | American University | Lafayette | 4.5 | 10 | Patriot QF, American -4.5 |
| 7 PM | ESPN+ | Boston University | Navy | 1.5 | 6 | Patriot QF, Boston University -1.5 |
| 7 PM | ESPN+ | Colgate | Army | 7.5 | 4 | Patriot QF, Army +7.5 |
| 7 PM | ESPN+ | Little Rock | UT Martin | 4.5 | 4 | OVC QF |
| 7 PM | ESPN+ | Murray State | Evansville | 5.5 | 5 | MVC Rd 1 |
| 7 PM | ESPN+ | Youngstown State | Purdue Fort Wayne | 1.5 | 0 | Horizon QF |
| 7 PM | ESPN+ | North Alabama | Jacksonville | 6.5 | 6 | Atlantic Sun Semis |
| 7:30 PM | ESPN+ | Sam Houston State | UTEP | 2.5 | 0 | |
| 7:30 PM | ESPN+ | Louisiana Tech | New Mexico State | 5.5 | 4 | |
| 7:30 PM | CBSSN | Middle Tennessee | Liberty | 1.5 | 1 | |
| 8 PM | FS1 | Iowa | #8 Michigan State | -6.5 | -13 | Michigan State -6.5 |
| 8 PM | ESPN+ | Milwaukee | Oakland | 6.5 | 9 | Horizon QF |
| 8 PM | ESPN+ | Robert Morris | Wright State | 6.5 | 10 | Horizon QF, Robert Morris -6.5 |
| 8 PM | ESPN+ | Cleveland State | Northern Kentucky | 3.5 | 7 | Horizon QF, Cleveland St -3.5 |
| 8 PM | ESPN+ | Lipscomb | Queens University | 9.5 | 7 | |
| 8 PM | ESPN+ | Western Kentucky | Florida International | 7.5 | 6 | |
| 8:30 PM | ESPN+ | Texas State | Old Dominion | 6.5 | 6 | Sun Belt Rd 3 |
| 9:30 PM | St. Thomas-Minnesota | Denver | 10.5 | 11 | Summit QF | |
| 9:30 PM | ESPN+ | Tennessee State | Lindenwood | 3.5 | 2 | OVC QF |
| 9:30 PM | ESPN+ | UIC | Valparaiso | 3.5 | 7 | MVC Rd 1, UIC -3.5 |