#ppiupsetalert record: 10-24 (.294)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | ESPN+ | La Salle | Dayton | -9.5 | -4 | La Salle +9.5 |
| 7 PM | BTN | #11 Illinois | Maryland | 18.5 | 12 | Maryland +18.5 |
| 7 PM | ESPN2 | #22 North Carolina | Notre Dame | 13.5 | 14 | |
| 7 PM | CBSSN | Drake | Murray State | -4.5 | -6 | |
| 7 PM | ESPN+ | Bradley | Indiana State | 8.5 | 11 | |
| 7 PM | ESPN+ | Richmond | Rhode Island | 3.5 | 9 | Richmond -3.5 |
| 7 PM | ESPN+ | Davidson | Fordham | 4.5 | 10 | Davidson -4.5 |
| 7 PM | Peacock | Villanova | Georgetown | 8.5 | 13 | Villanova -8.5 |
| 7 PM | FS1 | Creighton | Xavier | 7.5 | 3 | Xavier +7.5 |
| 7 PM | ACCN | Boston College | Pittsburgh | -2.5 | 2 | Boston College +128 |
| 7 PM | SECN | Kentucky | Texas | 7.5 | 4 | Texas +7.5 |
| 8 PM | ESPN+ | Valparaiso | Southern Illinois | 2.5 | 4 | |
| 8 PM | ESPN+ | UT-Arlington | Tarleton State | 3.5 | 6 | |
| 8:30 PM | ESPN+ | Southern Utah | Utah Valley | -12.5 | -10 | |
| 9 PM | FS1 | #1 Arizona | Cincinnati | 12.5 | 20 | Arizona -12.5 |
| 9 PM | BTN | #7 Nebraska | Washington | 10.5 | 20 | Nebraska -10.5 |
| 9 PM | ESPN+ | #8 Gonzaga | Pepperdine | 22.5 | 19 | Pepperdine +24.5 |
| 9 PM | ESPNU | Illinois State | Northern Iowa | 6.5 | 3 | Northern Iowa +6.5 |
| 9 PM | CBSSN | New Mexico | Fresno State | 15.5 | 14 | |
| 9 PM | Peacock | Arizona State | West Virginia | 2.5 | 3 | |
| 9 PM | ACCN | Syracuse | Virginia Tech | 3.5 | 1 | |
| 9 PM | SECN | Texas A&M | Mississippi State | 6.5 | 7 | |
| 9:30 PM | ESPN+ | San Diego | Washington State | -1.5 | 1 | |
| 10 PM | ESPN+ | Seattle | Loyola Marymount | 4.5 | 7 | |
| 10 PM | ESPN+ | California Baptist | Utah Tech | 8.5 | 9 | |
| 11 PM | CBSSN | Saint Mary’s | Oregon State | 19.5 | 18 | |
| 11 PM | BTN | USC | Northwestern | 6.5 | 8 | |
| 11 PM | FS1 | Grand Canyon | San Diego State | -1.5 | 3 | Grand Canyon -108 |