#ppiupsetalert record: 13-27 (.325)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | FS1 | #22 St. John’s | Xavier | 16.5 | 15 | |
| 7 PM | ESPN | #24 Louisville | NC State | 6.5 | 4 | |
| 7 PM | ESPN+ | Indiana State | Southern Illinois | 1.5 | 0 | |
| 7:30 PM | ESPN+ | Drake | Valparaiso | 3.5 | 3 | |
| 8 PM | ESPN+ | Evansville | Illinois State | -10.5 | -8 | |
| 8 PM | ESPN+ | Bradley | Belmont | -1.5 | -3 | |
| 8:30 PM | FS1 | Indiana | Oregon | 10.5 | 14 | Indiana -10.5 |
| 9 PM | ESPN | #11 Kansas | #1 Arizona | -1.5 | -2 | #ppiupsetalert, Kansas +108 |
| 10 PM | CBSSN | Murray State | Northern Iowa | 4.5 | 7 |