#ppiposseofpicks: 107-131 (.450)
#ppiupsetalert: 29-33 (.468)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | ESPN | #14 West Virginia | Missouri | 12.5 | 16 | |
| 12 PM | ESPNU | #16 Auburn | Iowa State | 8.5 | 12 | |
| 12 PM | FS1 | Michigan | #21 Illinois | 3.5 | 1 | #ppiupsetalert. Michigan -185 |
| 1 PM | CBS | Providence | #9 Villanova | 2 | -4 | #ppiupsetalert, Providence +112 |
| 2 PM | ACCNX | #6 Louisville | Clemson | 11 | 14 | |
| 2 PM | BTN | Rutgers | Nebraska | 14 | 16 | |
| 4 PM | ESPN | Kansas | Tennessee | 13.5 | 14 | |
| 4 PM | CBSSN | Memphis | SMU | 5.5 | 4 | #ppiupsetalert, SMU +5.5 |
| 6 PM | ESPN+ | Richmond | #7 Dayton | -6.5 | -2 | #ppiupsetalert, Richmond +230 |
| 6 PM | ESPN | #18 Texas Tech | #15 Kentucky | 4.5 | -2 | #ppiupsetalert, Kentucky +150 |
| 8 PM | ESPN | Florida | #1 Baylor | 1 | -3 | #ppiupsetalert, Florida -1 |
| 8 PM | ACCN | #5 Florida State | Notre Dame | 8 | 12 | |
| 9 PM | FS1 | #23 Colorado | Washington | 7.5 | 12 | |
| 9:30 PM | PAC12 | Arizona State | Arizona | -5 | 1 | #ppiupsetalert, Arizona St +170 |
| 10 PM | #2 Gonzaga | Pacific | 21 | 19 | ||
| 12 PM | NBCSN | La Salle | VCU | -9.5 | -4 | La Salle +9.5 |
| 2 PM | ESPN+ | Massachusetts | Duquesne | -5.5 | -7 | |
| 3 PM | St. Bonaventure | Rhode Island | -3 | 0 | #closegamealert, St. Bonaventure +120 | |
| 4 PM | ESPN+ | George Washington | Saint Joseph’s | 6 | 6 | |
| 6 PM | CBSSN | Davidson | George Mason | 7.5 | 1 | George Mason +320 |
| 12 PM | ESPN2 | North Carolina | Miami (FL) | 5.5 | 1 | Miami (FL) +195 |
| 12 PM | ACCN | Syracuse | Pittsburgh | 6.5 | 7 | |
| 2 PM | ESPNU | Boston College | Virginia Tech | -4 | -3 | |
| 4 PM | ACCNX | Georgia Tech | NC State | -1 | -1 | |
| 2 PM | ESPN+ | Pennsylvania | Temple | -1 | -3 | |
| 6 PM | ESPNU | East Carolina | Tulane | -1.5 | -3 | |
| 8 PM | ESPNU | Wichita State | UCF | 10 | 11 | |
| 2 PM | ESPN | Texas | LSU | -2 | -1 | |
| 2 PM | ESPN2 | Oklahoma | Mississippi State | 1.5 | 5 | |
| 4 PM | ESPNU | Texas A&M | Oklahoma State | -2.5 | 3 | Texas A&M +112 |
| 4 PM | ESPN2 | Arkansas | TCU | 6.5 | 6 | |
| 6 PM | ESPN2 | Alabama | Kansas State | 7 | 14 | Alabama -7 |
| 2 PM | FS1 | DePaul | St. John’s | 5 | 7 | |
| 9 PM | Idaho State | Montana State | -1 | -2 | ||
| 4:30 PM | ESPN3 | Central Michigan | Ball State | -2 | 1 | Central Michigan +110 |
| 5 PM | PAC12 | Oregon State | USC | 2.5 | -3 | USC +110 |
| 7 PM | PAC12 | Utah | Washington State | 6.5 | 6 | |
| 5:30 PM | SECN | Georgia | Ole MIss | 7 | 9 | |
| 8 PM | SECN | South Carolina | Vanderbilt | 11 | 7 |