#ppiposseofpicks: 98-123 (.443)
#ppiupsetalert: 26-31 (.456)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | CBSSN | Fordham | Davidson | -8.5 | -1 | Fordham +340 |
| 1 PM | BTN | Rutgers | Minnesota | 5 | 2 | |
| 6 PM | ESPNU | Cincinnati | East Carolina | 16.5 | 15 | |
| 6 PM | ACCN | Wake Forest | Boston College | 5.5 | 4 | |
| 8 PM | ESPNU | UCLA | California | 8.5 | 2 | California +350 |
#ppiposseofpicks: 95-117 (.448)
#ppiupsetalert: 23-28 (.451)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | FS1 | #14 Villanova | Connecticut | 10 | 13 | |
| 12 PM | ESPN2 | Oklahoma State | #2 Baylor | -6 | -7 | |
| 12 PM | FOX | St. John’s | #18 Seton Hall | -5 | -10 | Seton Hall -5 |
| 12 PM | ESPNU | Penn State | #21 Ohio State | 1 | 3 | #ppiupsetalert, Penn St -110 |
| 1 PM | DePaul | #5 Butler | -4 | -7 | ||
| 1 PM | ACCN | Miami (FL) | #9 Florida State | -6 | -5 | |
| 1:30 PM | CBS | Florida | #4 Auburn | 2 | -1 | #ppiupsetalert, Florida -140 |
| 2 PM | ESPN | Texas | #6 Kansas | -7 | -5 | |
| 2 PM | ESPNU | Kansas State | #12 West Virginia | -5.5 | -14 | West Virginia -5.5 |
| 2 PM | ESPN2 | #17 Maryland | Purdue | 5.5 | 8 | |
| 2:30 PM | Arizona | #20 Colorado | 6 | -2 | #ppiupsetalert, Colorado +220 | |
| 3:45 PM | CBS | Washington | #8 Oregon | -2 | -2 | #ppiupsetalert, Washington +110 |
| 4 PM | ESPN | Arkansas | #10 Kentucky | 1.5 | 8 | #ppiupsetalert, Arkansas -1.5 |
| 4 PM | ESPN2 | #16 Wichita State | Houston | 3.5 | 4 | #ppiupsetalert, Houston +3.5 |
| 4 PM | ESPNU | #23 Texas Tech | Iowa State | 7.5 | 5 | |
| 4:30 PM | FS1 | #25 Creighton | Providence | 7 | 7 | |
| 5 PM | BTN | #24 Illinois | Northwestern | 12 | 15 | |
| 6 PM | ESPN | #3 Duke | #11 Louisville | 8 | 7 | |
| 8 PM | CBSSN | #7 San Diego State | Nevada | 13 | 16 | |
| 10 PM | ESPN2 | Gonzaga | BYU | 13 | 10 | |
| 12:30 PM | NBCSN | Rhode Island | La Salle | 10.5 | 7 | |
| 2 PM | CBSSN | VCU | St. Bonaventure | 9 | 7 | |
| 2 PM | ESPN+ | Pennsylvania | Saint Joseph’s | 9 | 11 | |
| 2:30 PM | NBCSN | George Mason | Richmond | -2 | 1 | |
| 4:30 PM | NBCSN | Massachusetts | George Washington | 5.5 | 8 | |
| 12 PM | ESPN | Pittsburgh | North Carolina | 4 | 6 | |
| 12 PM | ACCNX | Virginia Tech | Syracuse | 4.5 | 5 | |
| 2 PM | NC State | Clemson | 6.5 | 7 | ||
| 8 PM | ACCN | Georgia Tech | Virginia | 0 | 3 | |
| 2 PM | ESPN3 | Tulane | Tulsa | 1 | 2 | |
| 6 PM | ESPNU | UCF | South Florida | 3.5 | 8 | UCF -3.5 |
| 8 PM | ESPNU | SMU | Temple | 5 | 5 | |
| 2 PM | ESPN+ | Oklahoma | TCU | 3.5 | 4 | |
| 2 PM | FS1 | Georgetown | Marquette | 4 | 5 | |
| 6 PM | Montana State | Eastern Washington | -1.5 | 0 | ||
| 7 PM | BTN | Nebraska | Indiana | -6 | -9 | |
| 4 PM | PAC12 | Washington State | Oregon State | -4 | -1 | |
| 6:30 PM | PAC12 | USC | Stanford | 2 | 2 | |
| 9 PM | PAC12 | Arizona State | Utah | 6.5 | 7 | |
| 1 PM | SECN | Texas A&M | South Carolina | 2 | 7 | Texas A&M -2 |
| 3:30 PM | SECN | Alabama | Missouri | 7 | 9 | |
| 6 PM | SECN | Vanderbilt | Tennessee | -5 | -2 | |
| 8 PM | ESPN2 | Ole Miss | LSU | -4 | -6 | |
| 8:30 PM | SECN | Mississippi State | Georgia | 6.5 | 4 |
#ppiposseofpicks: 95-116 (.450)
#ppiupsetalert: 23-27 (.460)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN2 | Saint Louis | #13 Dayton | 7.5 | 0 | #closegamealert, #ppiupsetalert, Saint Louis +275 |
| 7 PM | FS1 | #15 Michigan State | Wisconsin | 9.5 | 8 | |
| 9 PM | FS1 | Iowa | #19 Michigan | 4.5 | 5 |
#ppiposseofpicks: 95-114 (.455)
#ppiupsetalert: 23-26 (.469)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN | #22 Memphis | Cincinnati | 4.5 | 5 | |
| 9 PM | Washington State | #8 Oregon | -11 | -11 | ||
| 9 PM | ESPN2 | Arizona State | #20 Colorado | -2 | -2 | #ppiupsetalert, Arizona St +110 |
| 11 PM | ESPN2 | #1 Gonzaga | Santa Clara | 20 | 16 | |
| 8:30 PM | PAC12 | Arizona | Utah | 13 | 7 | Utah +13 |
| 10:30 PM | PAC12 | USC | California | 11.5 | 12 | |
| 11 PM | Washington | Oregon State | 4 | 4 |
#ppiposseofpicks: 93-110 (.458)
#ppiupsetalert: 22-26 (.458)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | FS1 | #5 Butler | #18 Seton Hall | 5 | 6 | |
| 6:30 PM | SECN | South Carolina | #10 Kentucky | -5.5 | -8 | |
| 7 PM | ESPN2 | #9 Florida State | Virginia | 6 | 11 | Florida St -6 |
| 7 PM | CBSSN | Georgetown | #25 Creighton | 2.5 | 3 | #ppiupsetalert, Georgetown -130 |
| 8 PM | ESPN+ | #2 Baylor | Iowa State | 9.5 | 13 | |
| 9 PM | ESPN2 | Alabama | #4 Auburn | -2 | -3 | |
| 9 PM | ESPNU | Temple | #16 Wichita State | -4.5 | -5 | |
| 7 PM | ESPN+ | Duquesne | Fordham | 17 | 18 | |
| 7 PM | ESPN+ | George Washington | George Mason | -3 | -10 | George Mason -3 |
| 7 PM | ESPN+ | St. Bonaventure | Massachusetts | 8.5 | 9 | |
| 7:30 PM | ESPN+ | Saint Joseph’s | Rhode Island | -8 | -9 | |
| 6:30 PM | ACCNX | Syracuse | Boston College | 12 | 7 | Boston College +12 |
| 7 PM | ACCNX | NC State | Miami (FL) | 8 | 3 | Miami (FL) +8 |
| 8:30 PM | ACCN | Georgia Tech | Notre Dame | 2 | 5 | |
| 7 PM | ESPN3 | East Carolina | Tulsa | -2.5 | -3 | |
| 9 PM | CBSSN | Houston | SMU | 8 | 7 | |
| 8 PM | ESPN+ | Oklahoma State | Texas | 3 | 4 | |
| 8 PM | Marquette | Xavier | 3 | 2 | ||
| 8:30 PM | FS1 | Providence | St. John’s | 5 | 4 | |
| 7 PM | BTN | Rutgers | Illinois | 3.5 | 2 | |
| 9 PM | BTN | Minnesota | Penn State | 2.5 | 3 | |
| 10 PM | PAC12 | UCLA | Stanford | -1.5 | -8 | Stanford -1.5 |
| 7 PM | ESPNU | Georgia | Tennessee | 2.5 | 3 | |
| 8:30 PM | SECN | Arkansas | Vanderbilt | 14 | 17 |
#ppiposseofpicks: 90-104 (.464)
#ppiupsetalert: 21-23 (.477)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 6:30 PM | FS1 | #21 Ohio State | Nebraska | 17.5 | 17 | |
| 7 PM | ESPN | Clemson | #3 Duke | -11 | -11 | |
| 7 PM | ACCN | Pittsburgh | #11 Louisville | -6 | -3 | #ppiupsetalert, Pittsburgh +180 |
| 8 PM | CBSSN | #13 Dayton | VCU | 8 | 11 | |
| 8 PM | ESPN+ | Kansas State | #23 Texas Tech | -3.5 | -1 | #ppiupsetalert, Kansas St +155 |
| 8:30 PM | FS1 | #14 Villanova | DePaul | 10.5 | 8 | |
| 9 PM | ESPN | Oklahoma | #6 Kansas | -6 | -1 | #ppiupsetalert, Oklahoma +230 |
| 9 PM | ESPNU | #12 West Virginia | TCU | 8 | 9 | |
| 9 PM | ESPN2 | Wisconsin | #17 Maryland | 3 | -1 | #ppiupsetalert, Wisconsin -145 |
| 11 PM | ESPN2 | Fresno State | #7 San Diego State | -6.5 | -17 | San Diego St -6.5 |
| 7 PM | ESPNU | Davidson | Richmond | 4 | -2 | Richmond +155 |
| 9 PM | ACCN | Wake Forest | Virginia Tech | -2.5 | 0 | Wake Forest +110 |
| 8 PM | ESPN3 | Tulane | UCF | 1 | 5 | Tulane -1 |
| 8 PM | BTN | Northwestern | Iowa | -5.5 | -8 | |
| 7 PM | ESPN+ | Eastern Michigan | Ball State | -3.5 | 3 | Eastern Michigan +155 |
| 7 PM | ESPN2 | Florida | Ole MIss | 10 | 10 | |
| 7 PM | SECN | Texas A&M | LSU | -6 | -2 | |
| 9 PM | SECN | Mississippi State | Missouri | 4 | 3 |
#ppiposseofpicks: 88-104 (.458)
#ppiupsetalert: 19-22 (.463)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | CBSSN | Connecticut | #23 Wichita State | -3 | -5 | #ppiupsetalert, Connecticut +3 |
| 12 PM | CBS | Purdue | #8 Michigan State | -4 | -4 | #ppiupsetalert, Purdue +4 |
| 4 PM | ESPN2 | South Florida | #21 Memphis | -3.5 | -3 | |
| 6 PM | ESPNU | #25 Colorado | Utah | 8.5 | 11 | |
| 10 PM | FS1 | Oregon State | #24 Arizona | -4 | 0 | #ppiupsetalert, Oregon St +160 |
| 6 PM | ACCN | Miami (FL) | Pittsburgh | 3 | 3 |
#ppiposseofpicks: 78-97 (.455)
#ppiupsetalert: 18-19 (.486)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | ESPNN | #5 Auburn | Georgia | 11 | 13 | |
| 12 PM | FOX | Indiana | #11 Ohio State | -2.5 | 2 | #ppiupsetalert, Indiana +115 |
| 12 PM | ESPN | #14 Kentucky | Alabama | 8.5 | 5 | #ppiupsetalert, Alabama +5 |
| 12 PM | FS1 | #16 Villanova | Georgetown | 7.5 | 4 | #ppiupsetalert, Georgetown +7.5 |
| 12:30 PM | NBCSN | #15 Dayton | Massachusetts | 19 | 20 | |
| 1 PM | CBS | #3 Kansas | #4 Baylor | 7.5 | 7 | |
| 2 PM | ESPN | Notre Dame | #13 Louisville | -3.5 | -1 | #ppiupsetalert, Notre Dame +155 |
| 2:15 PM | BTN | #20 Penn State | Wisconsin | 4 | 8 | |
| 4 PM | Loyola Marymount | #1 Gonzaga | -18.5 | -22 | ||
| 4 PM | ESPN | #18 Virginia | Syracuse | 7.5 | 8 | |
| 6 PM | ESPN | #17 West Virginia | #22 Texas Tech | 4.5 | 14 | West Virginia -4.5 |
| 8 PM | ACCN | #2 Duke | Wake Forest | 19 | 19 | |
| 10 PM | ESPN3 | #7 San Diego State | Boise State | 11 | 18 | San Diego State -11 |
| 10:30 PM | PAC12 | #9 Oregon | Arizona State | 10.5 | 11 | |
| 2 PM | CBSSN | VCU | Rhode Island | 8.5 | 11 | |
| 2 PM | ESPN+ | St. Bonaventure | Fordham | 12.5 | 13 | |
| 2 PM | ESPN+ | La Salle | George Mason | 3.5 | 2 | |
| 2:30 PM | NBCSN | Davidson | Saint Joseph’s | 15 | 12 | |
| 4 PM | ESPN+ | George Washington | Duquesne | -7 | -13 | Duquesne -7 |
| 6 PM | ESPN+ | Richmond | Saint Louis | 6 | 3 | |
| 2 PM | ACCNX | Virginia Tech | NC State | 2 | 2 | |
| 4:30 PM | ACCNX | North Carolina | Clemson | 4.5 | 7 | |
| 6 PM | ACCN | Boston College | Georgia Tech | -3.5 | 3 | Boston College +155 |
| 12 PM | ESPN2 | UCF | Cincinnati | -2.5 | 1 | |
| 12 PM | ESPNU | Temple | Tulane | 9.5 | 7 | |
| 2 PM | ESPNU | East Carolina | SMU | -8 | -12 | |
| 4 PM | ESPN2 | Tulsa | Houston | -6.5 | -6 | |
| 2 PM | ESPN2 | TCU | Oklahoma State | 3.5 | 7 | |
| 8 PM | ESPN2 | Iowa State | Oklahoma | 2.5 | -4 | Oklahoma +125 |
| 8 PM | LHN | Texas | Kansas State | 4.5 | 9 | |
| 12 PM | St. John’s | DePaul | 3.5 | -1 | ||
| 2 PM | FOX | Xavier | Creighton | 3.5 | 6 | |
| 4 PM | CBSSN | Seton Hall | Marquette | 6 | 11 | Seton Hall -6 |
| 12 PM | BTN | Illinois | Rutgers | 5.5 | 5 | |
| 4:30 PM | BTN | Northwestern | Nebraska | 5.5 | 4 | |
| 8 PM | Montana State | Portland State | 1 | 10 | Montana State -1 | |
| 6 PM | PAC12 | Stanford | Washington State | 10 | 15 | Stanford -10 |
| 8 PM | PAC12 | California | Washington | -6.5 | -4 | |
| 10 PM | ESPN2 | UCLA | USC | -1 | -6 | USC -1 |
| 1 PM | SECN | Tennessee | South Carolina | 6.5 | 11 | |
| 3:30 PM | SECN | Vanderbilt | Texas A&M | 5.5 | 3 | |
| 6 PM | SECN | Ole Miss | Arkansas | -2 | -7 | Arkansas -2 |
| 8 PM | ESPN | LSU | Mississippi State | 8 | 8 | |
| 8:30 PM | SECN | Missouri | Florida | -3 | -1 |
#ppiposseofpicks: 78-97 (.446)
#ppiupsetalert: 17-19 (.472)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | FS1 | Iowa | #12 Maryland | -2 | -4 | #ppiupsetalert, Iowa +115 |
| 9 PM | FS1 | Providence | #6 Butler | -2 | -7 | Butler -2 |
| 9 PM | CBSSN | Akron | Ball State | 3.5 | 11 | Akron -3.5 |
#ppiposseofpicks: 77-96 (.445)
#ppiupsetalert: 16-18 (.414)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | FS1 | #19 Michigan | Purdue | 5.5 | 5 | #ppiupsetalert, Purdue +5.5 |
| 7 PM | ESPN2 | #23 Wichita State | #21 Memphis | 4.5 | 6 | #ppiupsetalert, Wichita State -180 |
| 9 PM | ESPN2 | #8 Michigan State | Minnesota | 12.5 | 12 | |
| 9 PM | ESPN | #9 Oregon | #24 Arizona | 3.5 | 8 | |
| 10 PM | San Diego | #1 Gonzaga | -15 | -17 | ||
| 9 PM | FS1 | Stanford | Washington | 2.5 | 5 | |
| 9:30 PM | Idaho | Montana State | -3 | -7 | ||
| 10:30 PM | PAC12 | California | Washington State | 1 | 2 | |
| 11 PM | ESPNU | Oregon State | Arizona State | 4.5 | 4 |