#ppiposseofpicks: 23-26 (.469)
#ppiupsetalert: 4-8 (.333)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ACCN | Pittsburgh | Northern Illinois | 11.5 | 12 | |
| 7 PM | ESPN2 | Texas Tech | Southern Illinois | 23 | 13 | #ppiposseofpicks: Southern Illinois +23 |
| 8 PM | ESPN3 | Tulane | Alcorn State | 14 | 16 | |
| 8 PM | ESPN+ | North Dakota State | Montana State | 7.5 | 3 | #ppiposseofpicks: Montana State +270 |
#ppiposseofpicks: 21-23 (.477)
#ppiupsetalert: 4-8 (.333)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 4 PM | ACCN | #17 North Carolina | Wofford | 16 | 14 | |
| 6:30 PM | BTN | Minnesota | #3 Ohio State | -8 | -10 | |
| 3 PM | ESPN | Houston | Oklahoma State | 7 | -1 | #ppiposseofpicks: Oklahoma State +240 |
| 4:30 PM | PAC12 | Washington State | UC Riverside | 8.5 | 4 | #ppiposseofpicks: UC Riverside +8.5 |
| 6:30 PM | PAC12 | USC | Long Beach State | 18 | 21 | |
| 4 PM | BTN | Nebraska | Purdue | -12.5 | -11 | |
| 4 PM | ESPNU | Northwestern | SIU-Edwardsville | 20 | 20 | |
| 1 PM | ACCNX | Boston College | Central Connecticut State | 23.5 | 25 | |
| 1:30 PM | ACCNX | Virginia Tech | Gardner-Webb | 14.5 | 17 | |
| 3 PM | ESPN+ | UNC Greensboro | NC State | -2 | 1 | #ppiposseofpicks: UNC Greensboro +120 |
| 5 PM | ESPN2 | Clemson | South Carolina | 6 | 11 | #ppiposseofpicks: Clemson -6 |
| 4 PM | SECN | Missouri | Southern Illinois | 14.5 | 14 | |
| 6 PM | SECN+ | Texas A&M | Texas A&M-CC | 11.5 | 7 | #ppiposseofpicks: Texas A&M-CC +11.5 |
| 2 PM | ESPN3 | UCF | Sacred Heart | 10 | 12 | |
| 4 PM | ESPN3 | South Florida | Drexel | 10 | 11 | |
| 2 PM | ESPN+ | Fordham | Tennessee State | 3.5 | 3 | |
| 7 PM | ESPN+ | VCU | Missouri State | 11.5 | 13 |
#ppiposseofpicks: 13-16 (.448)
#ppiupsetalert: 3-4 (.429)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | ACCN | #1 Louisville | Eastern Kentucky | 32 | 30 | |
| 12 PM | CBS | #5 Michigan | #10 Oregon | 3.5 | 6 | |
| 12 PM | ESPN2 | Oakland | #16 Michigan State | -17 | -5 | #ppiposseofpicks: Oakland +17 |
| 12 PM | FS1 | #18 Butler | Southern University | 28.5 | 32 | #ppiposseofpicks: Butler -28.5 |
| 2 PM | ESPN2 | #20 Villanova | Delaware | 14.5 | 2 | #ppiupsetalert, #ppiposseofpicks: Delaware +14.5 |
| 3 PM | ESPN | #19 Tennessee | #13 Memphis | 7 | 3 | #ppiupsetalert, #ppiposseofpicks: Memphis +250 |
| 4 PM | ESPN2 | #12 Auburn | Saint Louis | 11 | 4 | #ppiupsetalert, #ppiposseofpicks: Saint Louis +11 |
| 4 PM | BTN | Rutgers | #22 Seton Hall | -2.5 | -5 | #ppiupsetalert, #ppiposseofpicks: Rutgers +2.5 |
| 4 PM | ACCN | Wake Forest | #23 Xavier | -5.5 | -8 | |
| 4:30 PM | ESPN+ | #2 Kansas | UMKC | 23.5 | 22 | |
| 5 PM | ESPN | #8 Kentucky | Georgia Tech | 15.5 | 8 | #ppiposseofpicks: Georgia Tech +15.5 |
| 7 PM | ESPN+ | #14 Dayton | Drake | 16 | 12 | #ppiposseofpicks: Drake +16 |
| 10 PM | ESPN2 | #15 Arizona | #6 Gonzaga | 2.5 | 0 | #ppiupsetalert, #closegamealert, #ppiposseofpicks: Gonzaga +120 |
| 11:30 AM | ESPNU | Mississippi State | Kansas State | 3 | 5 | |
| 2 PM | West Virginia | Nicholls State | 19.5 | 20 | ||
| 2 PM | LHN | Texas | Central Michigan | 14 | 15 | |
| 3 PM | TCU | Lamar | 16 | 10 | ||
| 6 PM | ESPN2 | Wichita State | Oklahoma | 4.5 | 4 | |
| 1 PM | FOX | Georgetown | Syracuse | 3 | 9 | #ppiposseofpicks: Georgetown -3 |
| 2 PM | FS1 | DePaul | UIC | 15 | 4 | #ppiupsetalert, #ppiposseofpicks: UIC +15 |
| 8 PM | FS1 | Providence | Stony Brook | 11.5 | 0 | #ppiupsetalert, #ppiposseofpicks: Stony Brook +11.5 |
| 3 PM | ABC | Notre Dame | UCLA | 6 | 7 | |
| 4 PM | PAC12 | Utah | Weber State | 9.5 | 11 | |
| 6 PM | PAC12 | Oregon State | Arkansas-Pine Bluff | 25.5 | 17 | #ppiposseofpicks: Arkansas-Pine Bluff +25.5 |
| 7 PM | CBSSN | San Jose State | Stanford | -16.5 | -17 | |
| 8 PM | PAC12 | Arizona State | Georgia | 4 | 12 | #ppiposseofpicks: Arizona State -4 |
| 10:30 PM | PAC12 | California | Saint Mary’s | -8.5 | -4 | |
| 2 PM | ACCN | Miami (FL) | Alabama A&M | 26 | 17 | |
| 2 PM | BTN | Penn State | Alabama | 12 | 14 | |
| 6 PM | BTN | Illinois | Old Dominion | 14 | 18 | |
| 1:30 PM | ESPNU | Arkansas | Tulsa | 12 | 11 | |
| 4 PM | ESPN3 | East Carolina | Campbell | 3 | -11 | #ppiposseofpicks: Campbell +3 |
| 3 PM | SECN | Ole Miss | Middle Tennessee | 0 | 15 | |
| 8 PM | SECN+ | Vanderbilt | Liberty | 1.5 | 1 | |
| 2 PM | Radford | Duquesne | -4.5 | -12 | ||
| 2 PM | ESPN+ | La Salle | Morgan State | 12.5 | 23 | |
| 5 PM | NBCSN | Richmond | Charleston | 8.5 | 12 |
#ppiposseofpicks: 13-16 (.448)
#ppiupsetalert: 3-4 (.429)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 8 PM | CBSSN | #24 Colorado State | Colorado | -4.5 | -2 | |
| 8 PM | BTN | Indiana | Nebraska | 16.5 | 22 | #ppiposseofpicks: Indiana -16.5 |
| 8 PM | FS1 | Creighton | UT-Rio Grande Valley | 18 | 18 |
#ppiposseofpicks: 13-16 (.448)
#ppiupsetalert: 3-4 (.429)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | West Virginia | Austin Peay | 15.5 | 18 | ||
| 8 PM | ESPN2 | Iowa State | Iowa | 4 | 5 |
#ppiposseofpicks: 10-15 (.400)
#ppiupsetalert: 2-4 (.333)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 8 PM | PAC12 | #15 Arizona | Omaha | 20 | 23 | |
| 9 PM | BTN | Illinois | #5 Michigan | 1 | -10 | #ppiupsetalert, #ppiposseofpicks: Illinois -115 |
| 7 PM | ESPN+ | Massachusetts | Yale | -4.5 | -4 | |
| 8:30 PM | ACCN | Virginia Tech | Chattanooga | 12.5 | 9 | |
| 8 PM | ESPN3 | Houston | UT-Arlington | 14 | 12 | |
| 8 PM | ESPN3 | Tulsa | Boise State | 2 | 4 | |
| 8 PM | TCU | Winthrop | 12.5 | 12 | ||
| 8 PM | ESPN+ | Kansas State | Alabama State | 20 | 11 | #ppiposseofpicks: Alabama State +20 |
| 7 PM | BTN | Rutgers | Wisconsin | 1 | 2 | |
| 10 PM | PAC12 | Arizona State | Prairie View A&M | 19 | 14 | #ppiposseofpicks: Prairie View A&M +19 |
| 10 PM | California | Fresno State | -1 | 12 | #ppiposseofpicks: California -105 |
#ppiposseofpicks: 8-11 (.421)
#ppiupsetalert: 1-3 (.250)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN | #1 Louisville | Texas Tech | 7 | 16 | #ppiposseofpicks: Louisville -7 |
| 7 PM | ESPN2 | Penn State | #4 Maryland | -1 | -3 | #ppiupsetalert, #ppiposseofpicks: Penn State +1 |
| 8 PM | ESPN+ | #2 Kansas | Milwaukee | 26 | 24 | |
| 9 PM | ESPN2 | #11 Baylor | #18 Butler | 5 | -4 | #ppiupsetalert, #ppiposseofpicks: Butler +200 |
| 9 PM | PAC12 | #24 Colorado | Northern Iowa | 10 | 9 | |
| 7 PM | FS1 | St. John’s | Brown | 12.5 | 17 | |
| 7 PM | ACCNX | Boston College | Albany | 6 | 12 | |
| 7 PM | ACCN | Notre Dame | Detroit Mercy | 20 | 18 | |
| 9 PM | ESPN | Indiana | Connecticut | 2.5 | 3 | |
| 7 PM | ESPNU | Temple | Saint Joseph’s | 14 | 24 | #ppiposseofpicks: Temple -14 |
| 8 PM | ESPN+ | UCF | Green Bay | 10.5 | 16 | |
| 12 PM | ESPN+ | Fordham | Bryant University | 6.5 | 9 | |
| 7 PM | ESPN+ | Davidson | Coppin State | 17.5 | 6 | #ppiposseofpicks: Coppin State +17.5 |
#ppiposseofpicks: 7-11 (.389)
#ppiupsetalert: 1-3 (.250)
| Time | Chan | Home | Away | Spread | Margin | |
| 8 PM | BTN | Iowa | Minnesota | 6.5 | 7 | |
| 7 PM | ESPN+ | Duquesne | Columbia | 11.5 | 25 | #ppiposseofpicks: Duquesne -11.5 |
#ppiposseofpicks: 5-6 (.455)
#ppiupsetalert: 1-3 (.250)
| Time | Chan | Home | Away | Spread | Margin | |
| 2 PM | ACCN | #17 Florida State | Clemson | 10.5 | 9 | |
| 4 PM | ACCN | #5 Virginia | #7 North Carolina | 4.5 | 5 | #ppiupsetalert, #ppiposseofpicks: North Carolina +4.5 |
| 4 PM | ESPNU | Saint Mary’s (N) | #19 Dayton (N) | -3.5 | 1 | #ppiupsetalert, #ppiposseofpicks: Saint Mary’s +145 |
| 7 PM | ESPN2 | #22 Washington | #9 Gonzaga | -4 | -3 | #ppiupsetalert, #ppiposseofpicks: Washington +155 |
| 7 PM | BTN | #11 Michigan State | Rutgers | 15 | 11 | |
| 9 PM | ESPN2 | Iowa State | #16 Seton Hall | 2 | -1 | #ppiupsetalert, #ppiposseofpicks: Seton Hall +2 |
| 5 PM | FS1 | DePaul | Buffalo | 9 | 21 | #ppiposseofpicks: Buffalo +21 |
| 2 PM | ESPNU | Oklahoma State | Wichita State | 5 | 9 | |
| 3 PM | ABC | Texas | Texas A&M | 9.5 | 13 | |
| 5 PM | PAC12 | UCLA | Denver | 18.5 | 15 | |
| 5 PM | BTN | Purdue | Northwestern | 13 | 12 | |
| 12 PM | ESPNU | South Carolina | Houston | -3 | -1 | #closegamealert, #ppiposseofpicks: South Carolina +135 |
| 4 PM | SECN | LSU | Northwestern State | 0 | 22 | |
| 1:30 PM | ESPN+ | Saint Louis | Tulane | -5.5 | 3 | #ppiposseofpicks: Tulane +190 |
| 2 PM | ESPN+ | Richmond | South Alabama | 7 | 12 | #ppiposseofpicks: Richmond -7 |
#ppiposseofpicks: 3-1 (.750)
#ppiupsetalert: 0-1 (.000)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | BTN | #6 Ohio State | Penn State | 7.0 | 6 | |
| 12 PM | ESPNU | #18 Baylor | #12 Arizona | 5.0 | -1 | #ppiupsetalert, #ppiposseofpicks: Arizona +170 |
| 12 PM | FOX | #24 Butler | Florida | 4.0 | 12 | #ppiposseofpicks: Butler -4 |
| 3 PM | ESPN2 | Saint Joseph’s | #23 Villanova | -15.5 | -16 | |
| 4 PM | #8 Kentucky | Fairleigh Dickinson | 20 | |||
| 5 PM | ESPN2 | #3 Maryland | Illinois | 10.5 | 18 | #ppiposseofpicks: Maryland -10.5 |
| 5:30 PM | CBSSN | UAB | #15 Memphis | -8.0 | -4 | #ppiupsetalert |
| 6 PM | #25 Utah State | Fresno State | 13.0 | 18 | ||
| 7 PM | ESPN2 | #2 Kansas | #20 Colorado | 9.5 | 0 | #ppiupsetalert, #closegamealert, #ppiposseofpicks: Colorado +9.5 |
| 7 PM | PAC12 | #13 Oregon | Hawaii | 19.0 | 16 | |
| 12 PM | FS1 | St. John’s | West Virginia | -4.5 | -7 | |
| 9 PM | ESPN2 | Kansas State | Marquette | 1.0 | -4 | #ppiposseofpicks: Marquette -105 |
| 3 PM | PAC12 | Washington State | New Mexico State | -4.0 | 5 | |
| 5 PM | Santa Clara | California | 5.0 | 1 | ||
| 5 PM | PAC12 | Utah | Central Arkansas | 17 | ||
| 9:30 PM | PAC12 | Arizona State | Louisiana Lafayette | 17.0 | 12 | |
| 2:30 PM | FS1 | Creighton | Nebraska | 11.5 | 14 | |
| 5 PM | FS1 | Xavier | Cincinnati | 6.0 | 8 | |
| 9:30 PM | ESPNU | SMU | Georgetown | 3.5 | 6 | |
| 12 PM | ACCN | Georgia Tech | Syracuse | 3.0 | 4 | |
| 2 PM | ESPNU | Notre Dame | Boston College | 12.5 | 12 | |
| 2 PM | ACCN | Wake Forest | NC State | 5 | 2 | |
| 4:30 PM | BTN | Wisconsin | Indiana | -1 | -7 | #ppiposseofpicks: Indiana -1 |
| 2 PM | SECN+ | Ole Miss | CSU Bakersfield | 16.5 | 14 | |
| 7:30 PM | ESPNU | Temple | Missouri | 4.5 | 12 | |
| 7:30 PM | CBSSN | Western Kentucky | Arkansas | -1.5 | -6 | |
| 12 PM | ESPN3 | UCF | NJIT | 19 | ||
| 3 PM | ESPN3 | Tulsa | Arkansas State | 11.5 | 11 | |
| 1 PM | ESPN+ | Harvard | Massachusetts | 9 | 4 | |
| 2 PM | ESPN+ | Fordham | Manhattan | 5 | 11 | |
| 2 PM | Drexel | La Salle | -2 | -5 | ||
| 2:30 PM | ESPN+ | St. Bonaventure | Hofstra | 3.5 | 4 | |
| 4 PM | Northeastern | Davidson | -1 | 4 | ||
| 4 PM | ESPN+ | George Washington | Delaware | -1.5 | -14 | #ppiposseofpicks: Delaware -1.5 |
| 7 PM | ESPN+ | George Mason | American University | 24 | ||
| 8 PM | ESPN+ | VCU | Old Dominion | 17 | ||
| 1 PM | ESPN+ | Ball State | IUPUI | 8 |