#ppiupsetalert record: 10-24 (.294)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | ESPN | Virginia Tech | #4 Duke | -12.5 | -3 | #ppiupsetalert, Virginia Tech +680 |
| 12 PM | FOX | #10 Houston | Cincinnati | 14.5 | 20 | Houston -14.5 |
| 12 PM | ESPN2 | UCF | #11 Texas Tech | -4.5 | -2 | #ppiupsetalert, UCF +164 |
| 12 PM | ACCN | #22 Clemson | Pittsburgh | 10.5 | 13 | |
| 12 PM | Peacock | Seton Hall | Marquette | 3.5 | 13 | Seton Hall -3.5 |
| 12 PM | TNT | Butler | Georgetown | 5.5 | 6 | |
| 12 PM | ACC Extra | Wake Forest | NC State | -4.5 | -5 | |
| 12 PM | ESPN+ | Toledo | Ball State | 7.5 | 12 | Toledo -7.5 |
| 1 PM | ESPN+ | Indiana State | Valparaiso | 2.5 | 0 | |
| 1 PM | CBS | Utah State | San Diego State | 6.5 | 11 | Utah State -6.5 |
| 1 PM | FS1 | Xavier | DePaul | 3.5 | 5 | |
| 1 PM | SECN+ | South Carolina | LSU | -3.5 | 5 | South Carolina +136 |
| 1 PM | SECN | Georgia | Texas A&M | 4.5 | 2 | |
| 1:30 PM | CW | Boston College | #17 Virginia | -12.5 | -10 | |
| 2 PM | TNT | Arizona State | #1 Arizona | -14.5 | -13 | |
| 2 PM | ACCN | Georgia Tech | #16 North Carolina | -10.5 | -5 | Georgia Tech +10.5 |
| 2 PM | ESPN | #20 Louisville | SMU | 9.5 | 5 | SMU +9.5 |
| 2 PM | ESPN+ | George Washington | Fordham | 10.5 | 11 | |
| 2 PM | FOX | Wisconsin | Ohio State | 4.5 | 10 | Wisconsin -4.5 |
| 2 PM | ESPN2 | Oklahoma | Texas | -1.5 | 3 | Oklahoma -102 |
| 2:30 PM | USA Net | La Salle | Saint Joseph’s | -2.5 | -2 | |
| 3 PM | Air Force | Fresno State | -9.5 | -5 | Air Force +9.5 | |
| 3 PM | ESPN+ | UT-Arlington | California Baptist | -2.5 | 1 | UT-Arlington +120 |
| 3:30 PM | ESPN+ | #24 Miami (OH) | Northern Illinois | 16.5 | 15 | |
| 3:30 PM | SECN | Missouri | Mississippi State | 6.5 | 2 | Mississippi State +6.5 |
| 4 PM | ESPN+ | Northern Iowa | Evansville | 11.5 | 13 | |
| 4 PM | ESPN2 | West Virginia | Baylor | 2.5 | 6 | West Virginia -2.5 |
| 4 PM | ACCN | Miami (FL) | California | 11.5 | 10 | |
| 4:30 PM | ESPN | #14 Kansas | #13 BYU | 3.5 | 6 | #ppiupsetalert, Kansas -170 |
| 4:30 PM | USA Net | Richmond | Davidson | 1.5 | 4 | |
| 5 PM | Peacock | UCLA | Indiana | 4.5 | 2 | |
| 5 PM | ESPN+ | Tarleton State | Utah Tech | 1.5 | 3 | |
| 6 PM | SECN | #18 Vanderbilt | Ole Miss | 10.5 | 10 | |
| 6 PM | CBSSN | Drake | Bradley | 1.5 | 1 | |
| 6 PM | ESPN+ | Washington State | Portland | 8.5 | 7 | |
| 6 PM | ESPN+ | San Diego | Oregon State | 2.5 | 2 | |
| 6 PM | ESPN2 | Utah | Oklahoma State | 1.5 | -2 | Oklahoma St -108 |
| 6 PM | ACCN | Florida State | Stanford | 3.5 | 1 | |
| 6 PM | CW | Syracuse | Notre Dame | 4.5 | 8 | Syracuse -4.5 |
| 6:30 PM | ESPN | #15 Arkansas | Kentucky | 6.5 | 11 | Arkansas -6.5 |
| 6:30 PM | USA Net | St. Bonaventure | George Mason | 1.5 | -2 | George Mason -104 |
| 7 PM | ESPN+ | Southern Illinois | UIC | 3.5 | 3 | |
| 7 PM | Peacock | USC | Rutgers | 12.5 | 9 | Rutgers +12.5 |
| 8 PM | FOX | Creighton | #2 Connecticut | -7.5 | -6 | |
| 8 PM | CBSSN | Belmont | Murray State | 3.5 | 7 | Belmont -3.5 |
| 8 PM | BTN | Northwestern | Washington | 1.5 | 4 | |
| 8:30 PM | ESPN | Tennessee | Auburn | 5.5 | -1 | Auburn +205 |
| 9 PM | ESPN+ | Loyola Marymount | Santa Clara | -9.5 | -7 | |
| 9:30 PM | FS1 | Wyoming | Colorado State | 1.5 | 0 | |
| 10 PM | CBSSN | San Jose State | New Mexico | -14.5 | -15 | |
| 10 PM | ESPN+ | San Francisco | Pacific | 5.5 | 6 | |
| 10:30 PM | ESPN | #6 Gonzaga | Saint Mary’s | 8.5 | 5 | Saint Mary’s +8.5 |