#ppiupsetalert record: 2-6 (.250)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | ESPN+ | Temple | St. Francis (PA) | 20.5 | 12 | St. Francis (PA) +20.5 |
| 12 PM | ACC Extra | Virginia Tech | Maryland-Eastern Shore | 27.5 | 21 | Maryland-Eastern Shore +27.5 |
| 1 PM | ESPN+ | #4 Iowa State | Eastern Illinois | 43.5 | 29 | Eastern Illinois +43.5 |
| 1 PM | BTN | Minnesota | Texas Southern | 20.5 | 10 | Texas Southern +20.5 |
| 2 PM | SECN | Missouri | Bethune-Cookman | 19.5 | 13 | Bethune-Cookman +19.5 |
| 2 PM | Campbell | Ball State | 8.5 | 11 | ||
| 2 PM | ESPN+ | Milwaukee | Indiana State | 4.5 | 3 | |
| 3 PM | BTN | Iowa | Western Michigan | 26.5 | 18 | |
| 4 PM | New Mexico | Florida Gulf Coast | 16.5 | 12 | Florida Gulf Coast +16.5 | |
| 5 PM | ACC Extra | Wake Forest | Queens University | 18.5 | 14 | Queens University +18.5 |
| 5 PM | ESPN+ | Loyola (CHI) | Chicago State | 13.5 | 4 | Chicago State +13.5 |
| 6 PM | Boise State | Saint Mary’s | -2.5 | -4 | ||
| 7 PM | SECN | Texas A&M | Jacksonville | 26.5 | 16 | |
| 7:30 PM | FS1 | USC | Washington State | 14.5 | 18 | USC -14.5 |