#ppiupsetalert record: 3-6 (.333)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 11 AM | ESPN+ | Fordham | New Haven | 12.5 | 1 | New Haven +750 |
| 2 PM | SECN+ | #25 Georgia | West Georgia | 20.5 | 18 | |
| 2 PM | ESPN+ | Butler | NJIT | 40.5 | 16 | NJIT +40.5 |
| 4 PM | SECN+ | South Carolina | South Carolina State | 31.5 | 20 | South Carolina St +31.5 |
| 6 PM | ACCN | #23 Virginia | American University | 26.5 | 15 | American +26.5 |
| 6 PM | BTN | Indiana | Siena | 22.5 | 8 | Siena +22.5 |
| 6:30 PM | ESPN+ | Georgetown | Coppin State | 33.5 | 23 | Coppin State +33.5 |
| 7 PM | SECN | LSU | Prairie View A&M | 29.5 | 18 | Prairie View A&M +29.5 |
| 7 PM | ESPN+ | Temple | Princeton | 8.5 | 10 | |
| 7 PM | ACC Extra | Florida State | Jacksonville | 24.5 | 10 | Jacksonville +24.5 |
| 7 PM | ESPN+ | Saint Joseph’s | Coastal Carolina | 6.5 | 3 | Coastal Carolina +6.5 |
| 7 PM | ESPN+ | West Virginia | Mississippi Valley State | 41.5 | 21 | Miss Valley St +41.5 |
| 7 PM | ACC Extra | Syracuse | Stonehill | 22.5 | 20 | |
| 7 PM | ESPN+ | Rhode Island | Northeastern | 10.5 | 10 | |
| 7 PM | ESPN+ | Duquesne | Canisius | 18.5 | 4 | Canisius +18.5 |
| 7 PM | ESPN+ | VCU | Rider | 30.5 | 18 | Rider +30.5 |
| 7 PM | ACC Extra | Boston College | Fairleigh Dickinson | 16.5 | 16 | |
| 8 PM | ACCN | #12 North Carolina | East Carolina | 25.5 | 26 | |
| 8 PM | ESPN+ | #17 Kansas | Davidson | 15.5 | 13 | |
| 8 PM | FS1 | #18 Illinois | Missouri | 10.5 | 3 | #ppiupsetalert, Missouri +440 |
| 8 PM | Memphis | Alabama State | 19.5 | 11 | Alabama St +19.5 | |
| 8 PM | BTN | Wisconsin | Central Michigan | 26.5 | 15 | Central Michigan +26.5 |
| 8 PM | Grand Canyon | IU Indianapolis | 23.5 | 23 | ||
| 8 PM | SECN+ | Texas | Maryland-Eastern Shore | 33.5 | 15 | Maryland-Eastern Shore +33.5 |
| 8 PM | ESPN+ | Creighton | Utah Tech | 19.5 | 11 | Utah Tech +19.5 |
| 9 PM | ESPN+ | #1 Arizona | Bethune-Cookman | 38.5 | 28 | Bethune-Cookman +38.5 |
| 9 PM | ESPN+ | #10 BYU | Eastern Washington | 34.5 | 26 | Eastern Washington +34.5 |
| 9 PM | SECN | Oklahoma | Stetson | 31.5 | 20 | Stetson +31.5 |
| 10 PM | BTN | Washington | San Diego | 18.5 | 10 | San Diego +18.5 |
| 10 PM | ESPN+ | Saint Mary’s | Northern Iowa | 11.5 | 8 | Northern Iowa +11.5 |