#ppiupsetalert record: 3-7 (.300)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 3 PM | BTN | #18 Illinois | Southern University | 33.5 | 20 | Southern +33.5 |
| 5 PM | BTN | Iowa | UMass Lowell | 32.5 | 24 | UMass Lowell +32.5 |
| 6 PM | SECN | #24 Florida | Dartmouth | 35.5 | 15 | Dartmouth +35.5 |
| 7 PM | B1G+ | #6 Purdue | Kent State | 25.5 | 16 | Kent State +25.5 |
| 7 PM | B1G+ | #2 Michigan | McNeese | 23.5 | 18 | McNeese +23.5 |
| 7 PM | FS1 | #9 Michigan State | Cornell | 26.5 | 21 | Cornell +26.5 |
| 7 PM | SECN+ | #13 Vanderbilt | New Haven | 39.5 | 30 | New Haven +39.5 |
| 7 PM | SECN+ | #25 Georgia | Long Island | 30.5 | 15 | Long Island +30.5 |
| 7 PM | ESPN+ | Murray State | Southern Illinois | 6.5 | 11 | Murray State -6.5 |
| 7 PM | ESPN+ | Indiana State | Belmont | -7.5 | -9 | |
| 7 PM | BTN | Rutgers | Delaware State | 20.5 | 20 | |
| 7 PM | ESPN+ | Cincinnati | Lipscomb | 13.5 | 3 | Lipscomb +13.5 |
| 7:30 PM | SECN+ | Mississippi State | Alabama State | 19.5 | 15 | Alabama St +19.5 |
| 8 PM | ESPN+ | #4 Iowa State | Houston Christian | 34.5 | 26 | Houston Christian +34.5 |
| 8 PM | SECN+ | #16 Alabama | Yale | 15.5 | 11 | Yale +15.5 |
| 8 PM | SECN+ | #14 Arkansas | James Madison | 23.5 | 16 | James Madison +23.5 |
| 8 PM | ESPN+ | Northern Iowa | Valparaiso | 10.5 | 13 | |
| 8 PM | ESPN+ | Bradley | Evansville | 11.5 | 15 | Bradley -11.5 |
| 8 PM | SECN | Ole Miss | Alcorn State | 27.5 | 11 | Alcorn St +27.5 |
| 8 PM | SECN+ | LSU | Southern Miss | 19.5 | 17 | |
| 8 PM | SECN+ | Texas A&M | Prairie View A&M | 29.5 | 16 | Prairie View A&M +29.5 |
| 8 PM | SECN+ | Oklahoma | Mississippi Valley State | 44.5 | 26 | Mississippi Valley St +44.5 |
| 8 PM | ESPN+ | Oklahoma State | Bethune-Cookman | 20.5 | 16 | Bethune-Cookman +20.5 |
| 8 PM | ESPN+ | TCU | Jackson State | 31.5 | 18 | Jackson St +31.5 |
| 8 PM | ESPN+ | #8 Houston | Middle Tennessee | 26.5 | 15 | Middle Tennessee +26.5 |
| 9 PM | ESPN+ | #1 Arizona | South Dakota State | 31.5 | 24 | South Dakota St +31.5 |
| 9 PM | ESPN+ | Drake | Illinois State | -2.5 | -3 | |
| 9 PM | BTN | Minnesota | Fairleigh Dickinson | 25.5 | 19 | Fairleigh Dickinson +25.5 |
| 10 PM | SECN | #21 Auburn | Queens University | 24.5 | 15 | Queens University +24.5 |
| 11 PM | FS1 | Washington | Utah | 10.5 | 8 |