#ppiupsetalert record: 0-2 (.000)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 1 PM | ESPN2 | #21 Kansas | Missouri | 5.5 | 1 | #ppiupsetalert, Missouri +5.5 [@ Kansas City, MO] |
| 2 PM | SECN | #12 Alabama | UTSA | 32.5 | 25 | UTSA +32.5 |
| 2 PM | ESPN+ | Charlotte | Utah State | -11.5 | -11 | |
| 3 PM | ESPN2 | LSU | #19 Texas Tech | -5.5 | 4 | LSU +184 |
| 4 PM | SECN | Mississippi State | San Francisco | 4.5 | 3 | |
| 4 PM | ACC Extra | Stanford | UNLV | 9.5 | 8 | |
| 4 PM | ACCN | Pittsburgh | Hofstra | 8.5 | 5 | Hofstra +8.5 |
| 5 PM | ESPN | #16 North Carolina | Georgetown | 10.5 | 9 | |
| 5 PM | ESPN+ | Washington State | Nevada | -2.5 | -9 | Nevada -2.5 |
| 5 PM | FS1 | Nebraska | Creighton | 5.5 | 8 | |
| 5 PM | ESPN2 | Texas A&M | SMU | 1.5 | -2 | SMU -104 |
| 5:30 PM | ESPN+ | North Texas | TCU | -9.5 | -1 | North Texas +9.5 |
| 9 PM | ESPN+ | #11 Gonzaga | North Florida | 46.5 | 31 | North Florida +46.5 |