#ppiposseofpicks: 8-11 (.421)
#ppiupsetalert: 1-3 (.250)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 7 PM | ESPN | #1 Louisville | Texas Tech | 7 | 16 | #ppiposseofpicks: Louisville -7 |
| 7 PM | ESPN2 | Penn State | #4 Maryland | -1 | -3 | #ppiupsetalert, #ppiposseofpicks: Penn State +1 |
| 8 PM | ESPN+ | #2 Kansas | Milwaukee | 26 | 24 | |
| 9 PM | ESPN2 | #11 Baylor | #18 Butler | 5 | -4 | #ppiupsetalert, #ppiposseofpicks: Butler +200 |
| 9 PM | PAC12 | #24 Colorado | Northern Iowa | 10 | 9 | |
| 7 PM | FS1 | St. John’s | Brown | 12.5 | 17 | |
| 7 PM | ACCNX | Boston College | Albany | 6 | 12 | |
| 7 PM | ACCN | Notre Dame | Detroit Mercy | 20 | 18 | |
| 9 PM | ESPN | Indiana | Connecticut | 2.5 | 3 | |
| 7 PM | ESPNU | Temple | Saint Joseph’s | 14 | 24 | #ppiposseofpicks: Temple -14 |
| 8 PM | ESPN+ | UCF | Green Bay | 10.5 | 16 | |
| 12 PM | ESPN+ | Fordham | Bryant University | 6.5 | 9 | |
| 7 PM | ESPN+ | Davidson | Coppin State | 17.5 | 6 | #ppiposseofpicks: Coppin State +17.5 |