#ppiupsetalertrecord: 4-4 (50.0%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | FS1 | #2 Connecticut | Georgetown | 23 | 29 | Connecticut -23 |
| 8:30 PM | PAC12 | #5 Arizona | Montana State | 21.5 | 18 | |
| 5 PM | #15 Mississippi State (N) | Drake (N) | 4.5 | 6 | ||
| 6:30 PM | ACCN | Wake Forest | #14 Duke | -7.5 | -7 | |
| 7 PM | SECN | #9 Alabama | Jackson State | 29.5 | 22 | Jackson State +29.5 |
| 7 PM | BTN | #18 Indiana | Elon | 28.5 | 30 | |
| 7 PM | Providence | #24 Marquette | 1.5 | -1 | #ppiupsetalert, Providence -111 | |
| 8 PM | ESPN+ | #12 Baylor | Northwestern State | 27.5 | 10 | Northwestern State +27.5 |
| 8:30 PM | ACCN | #22 Miami (FL) | #6 Virginia | -3.5 | 5 | #ppiupsetalert, Miami (FL) +130 |
| 9 PM | #11 Gonzaga | Montana | 23.5 | 21 | ||
| 2 PM | ESPN+ | Texas A&M | Wofford | 14.5 | 16 | |
| 2 PM | ESPN+ | Ole Miss | North Alabama | 22.5 | 15 | North Alabama +22.5 |
| 4 PM | ESPN+ | Oklahoma State | Texas A&M-Corpus Christi | 17.5 | 16 | |
| 6 PM | ESPN+ | Louisville | Lipscomb | -1.5 | -3 | |
| 7:30 PM | Nebraska | Queens University | 10.5 | 7 | ||
| 8:30 PM | Xavier | Seton Hall | 7.5 | 7 | ||
| 9 PM | ESPNU | Syracuse | Pittsburgh | 4.5 | 6 | |
| 9 PM | BTN | Northwestern | UIC | 14.5 | 12 | |
| 9:30 PM | ESPN2 | Oklahoma (N) | Florida (N) | -2.5 | 5 | Oklahoma +126 |
| 10:30 PM | Oregon | Utah Valley | 11.5 | 12 |