#ppiupsetalertrecord: 4-6 (.400)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 2 PM | Southern Miss | #25 Ole Miss | -9.5 | -12 | ||
| 3 PM | FOX | #4 Arizona | #14 Florida Atlantic | 6.5 | 4 | #ppiupsetalert, Florida Atlantic +6.5 (@ Las Vegas, NV) |
| 4 PM | CBS | #23 Memphis | Vanderbilt | 16.5 | 29 | Memphis -16.5 |
| 8 PM | FOX | #5 Connecticut | St. John’s | 11.5 | 6 | St. John’s +11.5 |
| 12 PM | FS1 | Providence | Butler | 6.5 | 6 | |
| 12 PM | BTN | Rutgers | Mississippi State | -3.5 | -6 | |
| 1 PM | ACCN | NC State | Detroit Mercy | 23.5 | 30 | NC State -23.5 |
| 1 PM | ESPN+ | West Virginia | Toledo | 4.5 | -8 | Toledo +158 |
| 2 PM | FS1 | Xavier | Seton Hall | 3.5 | 2 | |
| 4 PM | FS1 | DePaul | Villanova | -11.5 | -17 | Villanova -11.5 |
| 4 PM | SECN | Alabama | Eastern Kentucky | 24.5 | 21 | Eastern Kentucky +24.5 |