#ppiupsetalertrecord 11-10 (52.4%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 12 PM | FOX | #22 Xavier | #2 Connecticut | -2.5 | -5 | |
| 12 PM | ACCN | Georgia Tech | #13 Virginia | -9.5 | -6 | |
| 12 PM | ESPNU | #18 TCU | Texas Tech | 5.5 | 4 | |
| 12 PM | CBS | #19 Kentucky | Louisville | 22.5 | 19 | |
| 1 PM | ESPN2 | #17 Duke | Florida State | 17.5 | 22 | |
| 2 PM | ESPN+ | #3 Houston | UCF | 15.5 | 10 | UCF +15.5 |
| 2 PM | CBS | #4 Kansas | Oklahoma State | 10.5 | 13 | |
| 2 PM | FOX | Arizona State | #5 Arizona | -5.5 | 0 | #ppiupsetalert, Arizona State +5.5 |
| 2 PM | ESPN+ | Oklahoma | #6 Texas | -3.5 | 4 | #ppiupsetalert, Oklahoma +128 |
| 2 PM | ESPNU | Iowa State | #12 Baylor | -1.5 | -1 | |
| 4 PM | FS1 | Wyoming | #22 New Mexico | -2.5 | -17 | New Mexico -2.5 |
| 5 PM | #10 Gonzaga | Pepperdine | 20.5 | 19 | ||
| 7 PM | ESPN+ | Kansas State | #24 West Virginia | 1.5 | 4 | #ppiupsetalert, Kansas State -110 |
| 4 PM | ESPN+ | Montana State | Eastern Washington | 6.5 | 5 | |
| 12 PM | ACCNX | Wake Forest | Virginia Tech | -1.5 | 1 | |
| 12 PM | FS1 | Seton Hall | St. John’s | 3.5 | 2 | |
| 2 PM | ACCN | Syracuse | Boston College | 8.5 | 10 | |
| 2 PM | FS1 | Villanova | Marquette | 2.5 | -1 | |
| 4 PM | PAC12 | Stanford | Utah | 3.5 | -1 | |
| 6 PM | PAC12 | California | Colorado | -10.5 | -14 |