#ppiposseofpicks: 3-1 (.750)
#ppiupsetalert: 0-1 (.000)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | BTN | #6 Ohio State | Penn State | 7.0 | 6 | |
| 12 PM | ESPNU | #18 Baylor | #12 Arizona | 5.0 | -1 | #ppiupsetalert, #ppiposseofpicks: Arizona +170 |
| 12 PM | FOX | #24 Butler | Florida | 4.0 | 12 | #ppiposseofpicks: Butler -4 |
| 3 PM | ESPN2 | Saint Joseph’s | #23 Villanova | -15.5 | -16 | |
| 4 PM | #8 Kentucky | Fairleigh Dickinson | 20 | |||
| 5 PM | ESPN2 | #3 Maryland | Illinois | 10.5 | 18 | #ppiposseofpicks: Maryland -10.5 |
| 5:30 PM | CBSSN | UAB | #15 Memphis | -8.0 | -4 | #ppiupsetalert |
| 6 PM | #25 Utah State | Fresno State | 13.0 | 18 | ||
| 7 PM | ESPN2 | #2 Kansas | #20 Colorado | 9.5 | 0 | #ppiupsetalert, #closegamealert, #ppiposseofpicks: Colorado +9.5 |
| 7 PM | PAC12 | #13 Oregon | Hawaii | 19.0 | 16 | |
| 12 PM | FS1 | St. John’s | West Virginia | -4.5 | -7 | |
| 9 PM | ESPN2 | Kansas State | Marquette | 1.0 | -4 | #ppiposseofpicks: Marquette -105 |
| 3 PM | PAC12 | Washington State | New Mexico State | -4.0 | 5 | |
| 5 PM | Santa Clara | California | 5.0 | 1 | ||
| 5 PM | PAC12 | Utah | Central Arkansas | 17 | ||
| 9:30 PM | PAC12 | Arizona State | Louisiana Lafayette | 17.0 | 12 | |
| 2:30 PM | FS1 | Creighton | Nebraska | 11.5 | 14 | |
| 5 PM | FS1 | Xavier | Cincinnati | 6.0 | 8 | |
| 9:30 PM | ESPNU | SMU | Georgetown | 3.5 | 6 | |
| 12 PM | ACCN | Georgia Tech | Syracuse | 3.0 | 4 | |
| 2 PM | ESPNU | Notre Dame | Boston College | 12.5 | 12 | |
| 2 PM | ACCN | Wake Forest | NC State | 5 | 2 | |
| 4:30 PM | BTN | Wisconsin | Indiana | -1 | -7 | #ppiposseofpicks: Indiana -1 |
| 2 PM | SECN+ | Ole Miss | CSU Bakersfield | 16.5 | 14 | |
| 7:30 PM | ESPNU | Temple | Missouri | 4.5 | 12 | |
| 7:30 PM | CBSSN | Western Kentucky | Arkansas | -1.5 | -6 | |
| 12 PM | ESPN3 | UCF | NJIT | 19 | ||
| 3 PM | ESPN3 | Tulsa | Arkansas State | 11.5 | 11 | |
| 1 PM | ESPN+ | Harvard | Massachusetts | 9 | 4 | |
| 2 PM | ESPN+ | Fordham | Manhattan | 5 | 11 | |
| 2 PM | Drexel | La Salle | -2 | -5 | ||
| 2:30 PM | ESPN+ | St. Bonaventure | Hofstra | 3.5 | 4 | |
| 4 PM | Northeastern | Davidson | -1 | 4 | ||
| 4 PM | ESPN+ | George Washington | Delaware | -1.5 | -14 | #ppiposseofpicks: Delaware -1.5 |
| 7 PM | ESPN+ | George Mason | American University | 24 | ||
| 8 PM | ESPN+ | VCU | Old Dominion | 17 | ||
| 1 PM | ESPN+ | Ball State | IUPUI | 8 |