#ppiposseofpicks: 5-6 (.455)
#ppiupsetalert: 1-3 (.250)
| Time | Chan | Home | Away | Spread | Margin | |
| 2 PM | ACCN | #17 Florida State | Clemson | 10.5 | 9 | |
| 4 PM | ACCN | #5 Virginia | #7 North Carolina | 4.5 | 5 | #ppiupsetalert, #ppiposseofpicks: North Carolina +4.5 |
| 4 PM | ESPNU | Saint Mary’s (N) | #19 Dayton (N) | -3.5 | 1 | #ppiupsetalert, #ppiposseofpicks: Saint Mary’s +145 |
| 7 PM | ESPN2 | #22 Washington | #9 Gonzaga | -4 | -3 | #ppiupsetalert, #ppiposseofpicks: Washington +155 |
| 7 PM | BTN | #11 Michigan State | Rutgers | 15 | 11 | |
| 9 PM | ESPN2 | Iowa State | #16 Seton Hall | 2 | -1 | #ppiupsetalert, #ppiposseofpicks: Seton Hall +2 |
| 5 PM | FS1 | DePaul | Buffalo | 9 | 21 | #ppiposseofpicks: Buffalo +21 |
| 2 PM | ESPNU | Oklahoma State | Wichita State | 5 | 9 | |
| 3 PM | ABC | Texas | Texas A&M | 9.5 | 13 | |
| 5 PM | PAC12 | UCLA | Denver | 18.5 | 15 | |
| 5 PM | BTN | Purdue | Northwestern | 13 | 12 | |
| 12 PM | ESPNU | South Carolina | Houston | -3 | -1 | #closegamealert, #ppiposseofpicks: South Carolina +135 |
| 4 PM | SECN | LSU | Northwestern State | 0 | 22 | |
| 1:30 PM | ESPN+ | Saint Louis | Tulane | -5.5 | 3 | #ppiposseofpicks: Tulane +190 |
| 2 PM | ESPN+ | Richmond | South Alabama | 7 | 12 | #ppiposseofpicks: Richmond -7 |