#ppiupsetalertrecord 52-35 (59.8%)
| Time | Chan | Home | Away | Spread | Expected | Alerts |
| 6:30 PM | BTN | #1 Purdue | Penn State | 9.5 | 16 | Purdue -9.5 |
| 6:30 PM | FS1 | #16 Xavier | #17 Providence | 3.5 | -1 | #ppiupsetalert, Providence +146 |
| 7 PM | ESPN2 | Florida | #2 Tennessee | -5.5 | -5 | |
| 7 PM | SECN | #25 Auburn | Georgia | 11.5 | 14 | |
| 8:30 PM | FS1 | #14 Marquette | Villanova | 5.5 | 9 | |
| 6:30 PM | CBSSN | Georgetown | Creighton | -13.5 | -11 | |
| 7 PM | ACCN | North Carolina | Pittsburgh | 8.5 | 8 | |
| 7 PM | ACCNX | Louisville | Georgia Tech | -1.5 | -3 | |
| 8:30 PM | CBSSN | St. John’s | Seton Hall | -1.5 | 1 | |
| 8:30 PM | BTN | Rutgers | Minnesota | 14.5 | 13 | |
| 9 PM | ESPN2 | Oklahoma | Oklahoma State | 3.5 | 4 | |
| 9 PM | ACCN | NC State | Florida State | 9.5 | 14 | NC State -9.5 |
| 9 PM | SECN | Missouri | LSU | 10.5 | 9 | |
| 10:30 PM | FS1 | Utah State | New Mexico | 4.5 | 1 | |
| 6 PM | ESPN+ | UMass Lowell | Albany | 13.5 | 20 | UMass Lowell -13.5 |
| 7 PM | ESPN+ | Winthrop | Longwood | -3.5 | 1 | Winthrop +136 |
| 7 PM | ESPN+ | American University | Bucknell | 7.5 | 15 | American -7.5 |
| 7 PM | ESPN+ | Presbyterian College | Radford | -5.5 | -10 | Radford -5.5 |
| 7 PM | ESPN+ | Lehigh | Army | 1.5 | 10 | Lehigh -1.5 |
| 10 PM | ESPN+ | Seattle | Abilene Christian | 7.5 | 14 | Seattle -7.5 |