#ppiupsetalertrecord: 36-51 (41.4%)
| Time | Chan | Home | Away | Spread | Margin | Alerts |
| 12 PM | ESPN | #1 Auburn | Texas A&M | 12 | 22 | Auburn -12 |
| 12 PM | ESPN2 | #10 Baylor | #20 Texas | 6 | 11 | Baylor -6 |
| 12 PM | FS1 | Georgetown | Creighton | -4.5 | -7 | |
| 12 PM | SECN | Alabama | Arkansas | 5 | 4 | |
| 1 PM | CBS | #8 Kansas | Oklahoma | 10.5 | 13 | |
| 1 PM | FOX | #15 Villanova | Seton Hall | 9.5 | 13 | |
| 2 PM | ESPN+ | Montana State | Northern Arizona | 13.5 | 18 | Montana State -13.5 |
| 2 PM | ESPN3 | Buffalo | Ball State | 0 | 9 | |
| 2 PM | FS1 | #14 Wisconsin | Rutgers | 8 | 11 | Wisconsin -8 |
| 2 PM | ESPN | North Carolina | Florida State | 9 | 11 | |
| 2 PM | ESPN2 | Oklahoma State | West Virginia | 3.5 | 4 | |
| 2 PM | SECN | Georgia | South Carolina | -2.5 | -7 | |
| 3 PM | ACCNX | Wake Forest | Miami (FL) | 7.5 | 6 | |
| 3 PM | ACCN | Pittsburgh | NC State | -1.5 | 2 | |
| 3:30 PM | ABC | #6 Houston | Memphis | 10 | 8 | |
| 3:30 PM | FOX | #17 Michigan State | Indiana | 4 | 9 | Michigan State -4 |
| 4 PM | ESPN | #5 Kentucky | Florida | 9.5 | 12 | |
| 4 PM | ESPN+ | #9 Texas Tech | TCU | 10.5 | 7 | |
| 4 PM | ESPN+ | Morehead State | Murray State | -2.5 | -3 | |
| 4 PM | PAC12 | Oregon | California | 13.5 | 12 | |
| 4 PM | ESPN2 | Virginia | Georgia Tech | 9.5 | 11 | |
| 4 PM | ESPNU | Iowa State | Kansas State | 5.5 | 5 | |
| 4:30 PM | FS1 | Butler | #17 Marquette | -3.5 | -5 | Marquette -3.5 |
| 5 PM | ACCN | Boston College | #7 Duke | -13 | -14 | |
| 6 PM | PAC12 | Washington | #4 Arizona | -14 | -12 | |
| 6 PM | ESPN | Michigan | #16 Ohio State | 2.5 | 3 | |
| 6 PM | SECN | #19 Tennessee | Vanderbilt | 12 | 15 | |
| 6 PM | Santa Clara | San Francisco | -1.5 | 0 | ||
| 6 PM | ESPN2 | Virginia Tech | Syracuse | 0 | 4 | |
| 6:30 PM | FS1 | #11 Providence | DePaul | 9 | 13 | |
| 7 PM | ACCN | Clemson | Notre Dame | 2 | -4 | Notre Dame +110 |
| 8 PM | PAC12 | Colorado | Utah | 5 | 11 | Colorado -5 |
| 8 PM | ESPN2 | LSU | Mississippi State | 6 | 10 | |
| 8 PM | CBSSN | San Diego State | Air Force | 17.5 | 15 | |
| 8:30 PM | SECN | MIssouri | Ole Miss | 1 | 3 | |
| 8:30 PM | BTN | Minnesota | Penn State | 1 | 5 | |
| 9 PM | San Jose State | Wyoming | -12.5 | -13 | ||
| 10 PM | ESPN2 | #2 Gonzaga | #22 Saint Mary’s | 15.5 | 7 | Saint Mary’s +15.5 |
| 10 PM | ESPN | #21 USC | #12 UCLA | -2 | 3 | #ppiupsetalert, USC +108 |
| 10 PM | ESPNU | Washington State | Arizona State | 11.5 | 9 |